News

Women with current or past migraines were not seen to be at a higher risk of developing Parkinson’s disease in a recent study that analyzed data from a large U.S. clinical trial of women’s health. The risk was similar across the migraine types experienced by the women, including those with…

Inoviq’s Neuro-Net technology can aid in diagnosing Parkinson’s disease at early stages, with it having effectively isolated and identified brain-released exosomes, small vesicles whose information can act as disease fingerprints, in patients’ blood, the company announced. Measuring known biomarkers of the neurodegenerative disease using this technology enriched their…

Restoring the energy supply of nerve cells in the brain by activating a gene called PGK1 — which encodes an enzyme of the same name — could help protect these cells from damage and thus prevent Parkinson’s disease from developing or progressing over time, according to a new…

Levels of the trace metal selenium and its associated proteins, called selenoproteins, are altered in the blood of adults with Parkinson’s disease, a study reported. Two of these affected proteins, selenoprotein P (SelP) and selenoprotein S (SelS), were examined, and the researchers suggested that selenium and SelP levels could…

The nonprofit SPARK NS has announced the five recipients of the 2024 SPARK NS Parkinson’s Disease Translational Research Program that’s designed to foster the clinical development of promising therapies for Parkinson’s disease. The two-year program provides each scientist with up to $2 million, depending on the achievement…

Five top models for a wearable sensor that can monitor and measure freezing of gait (FOG) — a sudden inability to walk — in people with Parkinson’s disease were developed as the result of a three-month, international machine-learning contest launched by scientists at Tel Aviv University in Israel. The…

Adaptive deep brain stimulation (DBS) outperformed traditional DBS in alleviating motor symptoms and enhancing the quality of life for people with Parkinson’s disease, a pilot study shows. In adaptive DBS, nerve signals associated with motor fluctuations are detected in real time and stimulation is automatically adjusted to ease…

Cycling was more effective than electrical muscle stimulation at improving cognitive function, according to a small study. The results have implications for neurodegenerative diseases like Parkinson’s in which both movement and cognition can be affected. “Our results suggest that the relationship between exercise and brain activity is crucial for faster…

A complex of proteins involved in cellular trafficking, called the BBSome, plays a role in regulating the transport of dopamine, the nerve cell signaling molecule that’s deficient in Parkinson’s disease, a study reveals. “Given the significant medical impact of altered dopamine signaling in multiple neurobehavioral disorders, further studies of…

Enrollment is complete in a Phase 2 trial of VG081821, an investigational therapy to treat early to mid-stage Parkinson’s disease, the therapy’s developer, Vimgreen, announced. A total of 150 patients have been randomized to receive a low or high dose of VG081821 or a placebo for 12 weeks, or…