Video games carefully designed to improve the upper limbs — including grip strength, dexterity, and coordination — may be a rehabilitation aid for people with Parkinson’s disease (PD), a small study in patients suggests. The study, “Leap motion controlled video game-based therapy for upper limb rehabilitation in…
News
Inflammation in the gut, a hallmark of autoimmune disorders such as inflammatory bowel disease, may contribute to an earlier risk of developing Parkinson’s disease (PD), according to a recent review of genetic, epidemiological and animal model studies. The risk, however, is very small with only 3% to 5%…
There currently is not enough data to support the use of fecal transplants as a treatment in Parkinson’s disease, a new review suggests. Published in the Journal of Parkinson’s Disease, the review is titled “Faecal Transplantation, Pro- and Prebiotics in Parkinson’s Disease; Hope or Hype?”…
Enterin’s ENT-01, a compound that targets and reduces the accumulation of alpha-synuclein in nerve cells found in the gut, may slow the progression of Parkinson’s disease, according to a review study. The review, “Gastrointestinal Immunity and Alpha-Synuclein,” was published in the Journal…
A calcium channel called Cav2.3 plays a role in neuronal death, and may be a useful therapeutic target in Parkinson’s disease, suggests a new study done primarily in mice. The study, titled “Cav2.3 channels contribute to dopaminergic neuron loss in a model of Parkinson’s disease,” was published…
A new application for Android tablets, called SleepFit, may help to monitor the daily progression and response to treatment of motor symptoms associated with Parkinson’s disease, according to a study. The application was evaluated in the study “A New Prospective, Home-Based Monitoring of Motor Symptoms in Parkinson’s…
As part of a new partnership with Parkinson’s UK, the Parkinson’s Foundation has granted the nonprofit $250,000 toward a prospective new treatment linked to mitochondrial function that is being developed in the Parkinson’s Virtual Biotech program. The grant will help advance a project aimed at uncovering new methods…
A new biosensor system may make it easier to monitor stem cells changing into mature cells like neurons, which could allow for a better understanding of diseases like Parkinson’s and support the development of new treatments. The system was described in the paper, “Dual-Enhanced Raman Scattering-Based Characterization of…
Targeting Dopaminergic Neurons in ‘Zombie’ State Might Slow Parkinson’s Progression, Study Says
Contrary to what is commonly thought, dopamine-producing nerve cells (neurons) that stop functioning in Parkinson’s disease may not die, but instead enter a state of senescence in which they cease to divide and cause damage to healthy neighboring cells, a study found. In fact, one researcher noted these senescence cells…
Studies on gut bacteria in Parkinson’s disease differ in their findings and important methodological details, according to a new review that highlights these differences and proposes strategies to mitigate them in the future. The study, titled “Increasing Comparability and Utility of Gut Microbiome Studies in Parkinson’s Disease:…
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