News

Effort will automate ANPD001 cell therapy production for Parkinson’s

Mytos and Aspen Neuroscience are teaming up to automate the manufacture of autologous dopaminergic neuronal precursor cells (DNPCs) for ANPD001, Aspen’s experimental cell therapy program for Parkinson’s disease. As part of the agreement, Aspen will integrate Mytos’ iDEM automated cell culture technology into its new manufacturing…

Vyalev helped man sleep better at night, move during day: Report

Treatment with Vyalev (foscarbidopa and foslevodopa) eased motor symptoms and sleep disturbances in a 50-year-old man with Parkinson’s disease and a history of dream enactment behavior, according to a case report from Japan. Dream enactment behavior is a sign of rapid eye movement (REM) sleep disorder, in which…

New tool could show how genetic variants raise Parkinson’s risk

A new screening method may shed light on the interactions between genetic variants that increase the risk of Parkinson’s disease, providing potential avenues for improving risk prediction and personalized care, a study found. The tool, Variant-variant Interaction through Variable Thresholds (VARI3), is designed to detect and interpret how genetic…

Study unveils mechanisms behind levodopa-induced dyskinesia

The motor cortex, a brain region responsible for movement control, becomes disconnected in levodopa-induced dyskinesia (LID), the uncontrolled movements that occur as a side effect of the drug levodopa in Parkinson’s disease, a study found. Ketamine, an anesthetic used to alleviate LID, was found to restore the motor cortex’s…

Blood pressure treatment eases Parkinson’s tremor in small trial

Propranolol, a blood pressure medication, significantly eased tremor in people with Parkinson’s disease, either at rest or during induced stress, according to findings in a small, placebo-controlled clinical trial. The treatment also significantly attenuated tremor-related brain activity, as indicated on MRI scans. “In about forty percent of patients, […

As temperatures rise, risks climb for people with Parkinson’s

People with neurodegenerative diseases like Parkinson’s disease or dementia are more vulnerable to heat-related complications than those without these conditions, according to a commentary by two neurologists. Medical providers should be trained to understand how heat waves can affect these people, the viewpoint advised. It was co-written by Indu…