News

Structural changes — caused by a rare genetic mutation — to a protein called a dopamine transporter, which conveys dopamine into cells, may contribute to Parkinson’s disease-like symptoms, a study in fruit flies has found. Increasing the number of functional, or properly working, dopamine transporters in fruit flies…

Scientists have discovered how misfolded proteins in brain cells — those carrying mutations associated with Parkinson’s disease — spread to nearby healthy cells, a study reported.  These findings support the development of therapies that may prevent Parkinson’s progression, the researchers noted.

The U.S. Department of Veteran’s Affairs, known as the VA, has added atypical Parkinsonism to the list of conditions presumptively associated with Agent Orange exposure during military service. That will make U.S. military veterans who were exposed to Agent Orange eligible for the VA’s disability compensation benefits. Atypical Parkinsonism…

People with Parkinson’s disease made accurate self-reported diagnoses and expressed interest in virtually participating in research studies, according to a recent analysis from the ongoing Fox Insight study. That analysis was published in the journal Clinical Parkinsonism & Related Disorders, as a study called “Video-based Parkinson’s disease assessments…

Known to ease motor fluctuations due to “off periods” in Parkinson’s disease, daily use of Xadago (safinamide) at low dose also appears to significantly decrease such non-motor symptoms as apathy, while improving patients’ sense of motivation and interest over six months, a real-life study reported. The…

A new biobank in Sweden, containing blood samples from patients with Parkinson’s disease and age- and sex-matched healthy people — along with data regarding the individuals’ lifestyles and medical histories — may help researchers investigate the underlying mechanisms of the neurodegenerative disorder and find new treatments. The biobank is…

New exercise recommendations have been released by the Parkinson’s Foundation and the American College of Sports Medicine (ACSM) to provide effective and safe guidelines about physical activity for people with Parkinson’s disease and…

Levodopa, a standard treatment for Parkinson’s disease, reached the brain faster when given as a gel into the nasal cavity than as an intravenous (into-the-vein) injection, a new mouse study shows. The findings support the potential of intranasal administration as a way to reach the brain and bypass…

Whole-body electromyostimulation (WB-EMS) to trigger muscle contractions, improved upper and lower body strength, endurance, and hand-eye coordination in a small group of people with early Parkinson’s disease who did not engage in regular exercise programs. The study with that finding, “…