Long-term exposure to ozone, a form of air pollution, may increase the risk of developing Parkinson’s disease, according to a new study from Finland. “In this nationwide register study of long-term exposure to gaseous air pollutants and [Parkinson’s] risk, we observed a borderline statistically significant increased risk for [Parkinson’s]…
News
Fecal microbiota transplantation (FMT), a technique that uses processed stool from a healthy donor to help restore healthy bacteria in the gut, may provide a small, short-term improvement in daily motor activities for people with Parkinson’s disease, but current evidence does not show sustained benefits for overall motor function,…
Pretreatment with curcumin, a compound found in the spice turmeric, helped protect motor function in a mouse model of Parkinson’s disease, a new study found. Findings suggest that curcumin helped protect dopamine-producing nerve cells by activating autophagy, a process cells use to recycle unneeded material. This cellular recycling process,…
New funding from The Michael J. Fox Foundation for Parkinson’s Research (MJFF) will support lab studies of a one-time gene therapy candidate for Parkinson’s disease. Shape Therapeutics, a U.S. company that investigates RNA-based therapies, will use the newly awarded research grant to conduct preclinical studies of its…
The U.S. Food and Drug Administration (FDA) has granted regenerative medicine advanced therapy (RMAT) designation to sasineprocel (ANPD001), an experimental cell therapy to treat Parkinson’s disease. The designation, given to promising regenerative therapies (treatments that aim to replace or restore disease-damaged tissue) that could substantially improve care for serious diseases, …
Low dopamine levels disrupt nerve circuits in the brain in Parkinson’s disease — but a new study indicates that different brain circuits show different, even opposite, types of changes. The study’s findings shed new light on how brain circuits are affected by Parkinson’s. The researchers said their data also suggest…
Higher blood levels of a specific ratio between two fats, called ceramides, may help identify people with Parkinson’s disease who are more likely to develop thinking and memory problems, according to a new study. A higher Cer 24:1/Cer 24:0 ratio was closely associated with worsening cognitive impairment and remained…
Alzheimer’s-related brain changes may not be a major contributor to earlier cognitive problems in people with Parkinson’s disease who have not developed dementia, a new study suggests. Researchers found that blood levels of phosphorylated tau-217 (p-tau217), a blood marker of early Alzheimer’s disease, were not clearly associated with…
Patients participating in a three-week digital intervention program designed to complement levodopa, the standard treatment for Parkinson’s disease, showed measurable structural and functional changes in brain networks involved in movement, accompanied by meaningful easing of motor symptoms. The pilot study evaluated Remepy‘s investigational hybrid therapy, Hybridopa, in…
Language-based analyses of how people with Parkinson’s disease tell stories may provide a more nuanced look at how the disease affects memory and cognition, according to a study. In fact, the data suggest that a language-based approach can distinguish between people with or without Parkinson’s more accurately…
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