News

AbbVie Chooses Two Parkinson’s Therapies to Develop With Mission

AbbVie has selected two drug candidates — both targeting enzymes known as DUBs — for further development as possible Parkinson’s disease treatments, as part of the company’s ongoing collaboration with Mission Therapeutics. “We are delighted to have reached this next major milestone in our collaboration with AbbVie and…

Parkinson’s Foundation Grant Supports Free Dance-Pilates Classes

A $20,000 Parkinson’s Foundation community grant will help to keep the American Dance Festival’s (ADF) Parkinson’s Movement Initiative (PMI) going for a fifth year. The program, founded by ADF in 2017 with NC Dance for Parkinson’s, and Poe Wellness Solutions, is free for Parkinson’s disease (PD)…

MJFF Fellow Working to Raise Black, Minority Presence in Research

A Michael J. Fox Foundation (MJFF) research fellow is leading a study into the role of social determinants in medical mistrust and the lack of clinical trial participation by people with diseases such as Parkinson’s who belong to racial, ethnic and social minority groups. Paris Adkins-Jackson’s study, titled “…

CNM-Au8 Raises Cellular Energy in Brains of Patients in REPAIR-PD Trial

Clene Nanomedicine‘s investigational oral Parkinson’s treatment, CNM-Au8, safely and significantly increased energy metabolism in the brains of patients taking part in the Phase 2 REPAIR clinical trials, top-line results show. Greater energy metabolism is expected to lower oxidative stress in the brain, making more energy available to protect and…

New Algorithm Groups Parkinson’s Symptoms to Predict Progression

Researchers with IBM and the Michael J. Fox Foundation developed a computational model that may help physicians better understand how Parkinson’s disease will progress among individuals. In their study, the algorithm — based on a branch of computer science called machine learning — identified groups of Parkinson’s symptoms and…

Trial of Microbiota Transplant in Treating Patients Opens in Australia

BiomeBank is launching a trial in Australia to test whether its fecal microbiota transplantation therapy, which works to replenish gut bacteria, is a safe, tolerable and effective treatment of Parkinson’s disease symptoms, such as constipation. The trial is being conducted in collaboration with the Royal Adelaide and Queen Elizabeth hospitals…

Pathogens More Abundant in Mouths of Parkinson’s Patients

Opportunistic pathogens — microorganisms that live in us all,  but under specific circumstances can cause diseases like pneumonia — are more abundant in the mouths of people with Parkinson’s disease than healthy individuals, a study reported. This finding suggests that changes in oral bacteria in patients are related to disease…

Six miRNAs in Blood Show Potential as Biomarkers

Six microRNAs may serve as biomarkers of Parkinson’s disease progression and early diagnosis, a recent study suggests. That study, “Several miRNAs derived from serum extracellular vesicles are potential biomarkers for early diagnosis and progression of Parkinson’s disease,” was published in the journal Translational Neurodegeneration. MicroRNAs (miRNAs)…