News

COGNISANT Boosts Short-term Memory in Older Adults: Study

A new strategy that combines online cognitive therapeutic games with a noninvasive brain stimulation technique – called COGNISANT – may help boost short-term memory in older people, according to a new study. The findings may prove important for people with Parkinson’s disease who often experience a decline in short-term,…

At-home Digital Cameras Monitor Gait, May Speed Diagnosis

Researchers have developed a software that can accurately identify people with Parkinson’s disease or multiple sclerosis (MS) from healthy controls based solely on their gait. The software, which analyzes gait video data collected at patients’ homes using simple digital cameras, may provide an inexpensive tool to identify and…

MJFF Grant Supports Research of Brain Inflammation

Muna Therapeutics has received a $4.9 million grant from The Michael J. Fox Foundation for Parkinson’s Research (MJFF) to advance  development of its first-in-class small molecules used to halt neuroinflammation and restore nerve cell function in people with Parkinson’s disease. The grant will fund preclinical research into small molecules…

Smallest Clumps of Alpha-synuclein Protein Seen to Drive Parkinson’s

Alpha-synuclein protein clumps — the toxic aggregates related to nerve damage in Parkinson’s disease — vary, including in size, and small fragments appear to drive cellular toxicity compared with larger fragments, a study shows. Its findings were confirmed in post-mortem examinations of brain tissue from Parkinson’s patients, showing smaller clumps…

50 Parkinson’s Genes Found With New Multidisciplinary Approach

Fifty new genes that modified signs of Parkinson’s disease in a fruit fly model have been discovered using a multidisciplinary approach involving genomics, computational tools, and patient sample analysis, a study has reported. Some gene candidates worsened Parkinson’s signs while others conferred neuroprotection, “underscoring their therapeutic potential,” the researchers…

FDA Seeking Information Before OK of Apomorphine Infusion Device

The U.S. Food and Drug Administration (FDA) wants more information before it will approve Supernus Pharmaceuticals’ new drug application (NDA) resubmission of SPN-830, its apomorphine infusion pump. Supernus is seeking the approval of SPN-830 for the continuous treatment of “off” episodes in adults with Parkinson’s disease. These…

Faster Progression Found in ‘Body-involvement’ Parkinson’s in Study

People with Parkinson’s disease who show early dysfunction in the nerves controlling heartbeat tend to experience faster disease progression, a new study shows. According to researchers, these results support a new approach differentiating “brain-predominant” Parkinson’s from disease with “body-involvement.” “These findings correspond well to the results of…