A gene therapy tool dubbed AAV-DB-3, being developed by Latus Bio to deliver therapeutic genetic material into cells, is able to reach deep structures in the brain — among them ones that become damaged in neurodegenerative disorders such as Parkinson’s disease — a study in mice, monkeys, and lab-grown…
REM sleep behavior disorder (RBD) can mean restless nights for people with Parkinson’s disease and their partners, and add to symptoms, such as cognitive impairment and problems with blood pressure or digestion, that make daily life more difficult for both, a study shows. To ease any tension, couples often…
Unixell Biotechnology has dosed its first Parkinson’s disease patient in a clinical study of its stem cell therapy candidate, UX-DA001. According to a press release from Unixell, a surgeon at Ruijin Hospital in Shanghai successfully injected the experimental medication directly into a patient’s brain. UX-DA001 is derived from…
Risvodetinib, an experimental oral small molecule Abli Therapeutics is developing for people with untreated Parkinson’s disease, may be one step closer to Phase 3 clinical testing, following a meeting with U.S. regulators. The end-of-Phase 2 meeting’s main goal with the U.S. Food and Drug Administration (FDA) was to…
Walk in New York, a new clinic from Wandercraft, will allow people with Parkinson’s disease to access robotic-assisted training intended to help in the rehabilitation of patients’ walking ability. “Our mission has always been to restore everyday mobility, building hand in hand with the community of people…
Treatment with Askbio‘s gene therapy candidate AB-1005 is safe and appears to ease motor symptoms in people with either a recent or a long-standing diagnosis of Parkinson’s disease. That’s according to the full results of a small Phase 1 clinical trial conducted by the gene therapy’s developer at three…
The Michael J. Fox Foundation (MJFF) has awarded a $3.3 million research grant to Montara Therapeutics to develop a brain-selective therapy for Parkinson’s disease using the company’s Brainonly platform. As part of the project, Montara will design and develop an LRRK2 inhibitor drug candidate that can reach…
U.K.-based charity Cure Parkinson’s is marking its 20th anniversary by inviting supporters to take on walking challenges to raise money for Parkinson’s disease research and advocacy. “Our aim is to cure Parkinson’s and the only way we will do this is through the help of all our incredible supporters,” Helen…
A small molecule that blocks the interaction between two proteins could help protect nerve cells from premature death in neurodegenerative diseases such as Parkinson’s, a study found. Researchers at the Walter and Eliza Hall Institute (WEHI) in Australia discovered that a newly identified small molecule, WEHI-3773, prevents the protein…
Integrating movement sensors and machine learning approaches may aid a correct diagnosis of movement disorders, including essential tremor and myoclonus, a study in the Netherlands suggests. Essential tremor is a progressive movement disorder marked by tremors, while myoclonus refers to brief, shock-like muscle jerks. Both can occur during voluntary movements…
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