Nearly six months of a ketogenic diet, one low in carbohydrates and high in fat, eased motor symptoms and anxiety and depression while improving cognition in a woman with mild Parkinson’s disease, a case study found. These findings suggest that a ketogenic diet may offer an additional, non-pharmacological way…
A Stanford University research initiative will focus on the causes of neurodegeneration in diseases such as Parkinson’s and on the mechanisms behind some people’s brain resilience to aging and neurodegeneration. This information will be used to find ways to prevent, delay, or even reverse neurodegeneration and cognitive decline. “This…
A three-month community-based boxing program significantly eased motor and non-motor symptoms, as well as depression, in adults with early Parkinson’s disease, a pilot study showed. These preliminary findings support larger and longer studies into the benefits of such programs, which also could include people with more advanced disease. Results were…
Asceneuron’s experimental oral therapy ASN90 was found to significantly reduce the levels of toxic clumps of the alpha-synuclein protein — a hallmark of Parkinson’s disease — and improve motor function in a mouse model of the disease. The molecule — a suppressor of O–GlcNAcase (OGA), an enzyme involved…
During Parkinson’s Awareness Month, Aspen Neuroscience will launch a patient screening study to potentially advance ANPD001, its experimental, personalized neuron replacement therapy for Parkinson’s disease, into clinical trials. Considered to be the first of its kind, the Trial-Ready Cohort Study will involve several screening sites in the U.S.
Treatment with liraglutide — approved to treat type 2 diabetes and obesity — improved non-motor function and the ability to perform daily life activities in people with Parkinson’s disease, according to initial top-line data from a Phase 2 trial. The therapy, sold by Novo Nordisk under the brand names…
To celebrate Parkinson’s Awareness Month, this year’s INSIGHT into Parkinson’s meeting will be the longest World Parkinson’s Day conference to date and focus on research updates and practical suggestions to improve the lives of people with Parkinson’s disease. World Parkinson’s Day takes place on April 11, and April…
A real-time, home-monitoring system allowed for remote detection and management of orthostatic hypotension — a sudden drop in blood pressure when changing positions — in people with Parkinson’s disease during the COVID-19 pandemic, a pilot study shows. Notably, the eight patients involved reported these episodes profoundly affect daily life…
Multidisciplinary rehabilitation for Parkinson’s disease is associated with reduced disability and better functional status and quality of life relative to conventional rehabilitation, according to a review study. However, these differences failed to reach statistical significance. This means that either of the two approaches provide equivalent benefits, or the small number…
A protein involved in the transport of brain signaling molecules may confer protection against neurodegeneration in Parkinson’s disease, a study shows. This transport protein, called vesicular glutamate transporter 2 (VGLUT2), is associated with greater resilience to the toxic effects of alpha-synuclein clumps in dopamine-producing neurons, preventing their death. Dopamine…
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