P2B001 effective in key patient subgroups: Phase 3 trial data
P2B001, an investigational combination therapy (pramipexole/rasagiline) from Pharma Two B, controlled Parkinson’s disease symptoms better than either of…
Articles by Lindsey Shapiro, PhD
Variety of approved drugs target PINK1 protein, may aid Parkinson’s
An artificial intelligence (AI)-based algorithm identified more than a dozen U.S.-approved medications that might be repurposed to treat Parkinson’s…
Healthy level of exercise lacking in older women with Parkinson’s in US
Older women with Parkinson’s disease are more likely to be sedentary throughout the day, spending less time engaged in…
Dopamine neurons may be more diverse than thought
A specific subset of dopamine-producing nerve cells in the brain appear to respond to movement acceleration and correspond with the…
Bladder problems in patients linked to distinct brain networks on MRI
Parkinson’s disease patients with urinary incontinence (UI) exhibit distinct brain activity networks compared with patients without the bladder symptom,…
Legumes may lower risk of Parkinson’s symptoms with sleep disorder
A diet rich in legumes — a food group including beans, soybeans, and lentils — was associated with a lower…
LRRK2 mutations may curb certain immune cells’ ability to clear waste
Mutations in the LRRK2 gene might contribute to Parkinson’s disease by suppressing the activity of lysosomes, the cell compartments…
$300K awarded to Colorado scientist developing new treatments
A research lab at the University of Denver in Colorado has received $300,000 in funding from the Parkinson’s Foundation…
RORA protein may help explain Parkinson’s sex-related differences
A specific protein associated with sex hormone production may shed light on the sex-related differences in Parkinson’s disease observed…
Benefits of exercise in Parkinson’s rat study linked to neuroplasticity
Intensive treadmill exercise improved motor and cognitive function in a rat model of Parkinson’s disease and was linked to…