Scientists have found evidence that BMP5 and BMP7, two bone morphogenetic proteins (BMPs) that have been found to play a role in the development of dopamine-producing neurons, may help slow or even stop the progression of Parkinson’s disease. They discovered in a mouse model of Parkinson’s that the two…
Medtronic has launched a clinical trial to assess the safety and efficacy of adaptive deep brain stimulation, or aDBS, an investigational feature of its Percept PC Neurostimulator device, in people with Parkinson’s disease. Unlike conventional continuous deep brain stimulation, known as cDBS — in which electrical signals…
The levels of a specific RNA molecule that provides instructions to make the alpha-synuclein protein may help, at an early stage, to distinguish patients with Parkinson’s disease from those with dementia with Lewy bodies, a study has found. Researchers said these results highlight the importance of exploring the potential…
Note: This story was updated on Jan. 14, 2021, to note that DA01 is derived from ESCs and that the trial will take place at MSK in New York. The U.S. Food and Drug Administration (FDA) has cleared a request to open a Phase 1 clinical trial of DA01, an…
People with early Parkinson’s disease are at a higher risk of developing later cognitive problems if they are overweight, have symptoms of depression or anxiety, or have sleep issues or often feel sleepy during the day, a study has found. Recognizing these signs early on, and identifying those at…
An alternative method of recycling mitochondria — the cell’s powerhouses — that involves pushing damaged mitochondria out of cells, seems to play a role in Parkinson’s disease, according to a recent study. Researchers have found evidence in cellular and animal models of disease that this process is enhanced in the…
Older age, male sex, and a family history of Parkinson’s disease appear to associate with a higher risk of developing Parkinson’s later in life, according to an Italian study. The research also suggested that dietary choices and work history influenced the disease’s development, with those who consumed meat on…
Throughout 2020, Parkinson’s News Today brought you daily coverage of important discoveries, treatment advancements, preclinical and clinical studies, and other relevant events related to Parkinson’s disease. We are looking forward to bringing more news this year to those with Parkinson’s, their caregivers, and loved ones. Here we present our 10…
Patients with Parkinson’s disease are two times more likely to commit suicide than people from the general population, according to data from a Taiwanese population-based study. Importantly, this increased risk of self-inflicted death was found to be independent of socioeconomic status, dementia, and the presence of other mental disorders,…
Metabolic pathways involving uric acid and homocysteine may play a role in the onset of peripheral neuropathy in patients with Parkinson’s disease, a study suggests. The study, “Peripheral Neuropathy in de novo Patients with Parkinson’s Disease,” was published in the Yonsei Medical Journal. Peripheral…
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