Treatment with Askbio‘s gene therapy candidate AB-1005 is safe and appears to ease motor symptoms in people with either a recent or a long-standing diagnosis of Parkinson’s disease. That’s according to the full results of a small Phase 1 clinical trial conducted by the gene therapy’s developer at three…

A clinical trial testing the safety and tolerability of Brenig Therapeutics‘ BT-267, a potential disease-modifying therapy for Parkinson’s due to an unknown cause — known as idiopathic — or disease associated with LRRK2 gene mutations, has begun dosing healthy volunteers. Following this initial assessment — the first-in-human trial of…

Using IPX203, an extended-release formulation of carbidopa/levodopa (CD/LD), was associated with a sustained control of symptoms for Parkinson’s disease patients who participated in the open-label extension of the RISE-PD Phase 3 trial. Final results from the nine-month extension study (NCT03877510) indicate dose adjustments and side effects were…

I’m on the phone with a technology expert from the Los Angeles County Sheriff’s Department — the biggest sheriff’s department in the world — when the idea strikes me: Dad could use an Apple Watch to help monitor potential falls caused by his…

The winter of 2022 was spectacular here in southwestern Ontario. It was cold enough for our pond to freeze for the first time in many years. Most weekends were sunny and icy cold, and our extended family and friends would come to our farm for a skating party. When we…

Exposure to low oxygen may help to ease the symptoms of Parkinson’s disease — but a lot more research is needed to conclusively determine the safety and effectiveness of this strategy for use among people with the neurodegenerative disorder, according to a new report. “From a clinical perspective, hypoxia…

Increasing doses of KM-819, a potential therapy being developed by Fascinate Therapeutics for Parkinson’s disease, showed a favorable safety profile in healthy older adults, according to data from the now-completed Part 1a of a Phase 2 trial. The placebo-controlled trial (NCT05670782), which was launched last year, is…

Few things enable personal freedom as much as a car. When you live in the great automotive state of Michigan, just a short one-hour drive from the headquarters of companies like Ford and General Motors, this reality seems even starker. People use vehicles to go to the grocery store, church,…

Managing medications is a common responsibility for those with Parkinson’s disease and many other conditions. According to Georgetown University’s Health Policy Institute, more than 131 million people — 66% of U.S. adults — use prescription drugs. With Parkinson’s disease, managing medications is a balancing act required for us to…

Anyone who drives today knows that the roads and freeways can sometimes turn into a raceway! From drivers not using their turn signals to motorists cutting others off, countless challenges abound. But what if you have cognitive issues or slower reaction times? Should someone with Parkinson’s disease (PD) be driving?…