NE3107 added to levodopa enhances motor, non-motor benefits

Adding NE3107 to standard carbidopa/levodopa (CD/LD) therapy eases motor and non-motor symptoms in people with Parkinson’s disease, according to data from a Phase 2a trial. “These data suggest that NE3107 as an adjunct therapy to levodopa may hold promise in ameliorating specific non-motor symptoms of Parkinson’s Disease, particularly in sleep/fatigue…

Brain Ultrasound Signals Linked to Motor Disability, Gait

Enhanced ultrasound signals in the substantia nigra, the area of the brain impacted by Parkinson’s disease, are associated with increased motor disability and gait disturbances, a study concluded. The researchers noted that these ultrasound signals, called hyperechogenicity, may be useful a biomarker that reflects disease severity. “Our results may…