Argobio and GeneCode are teaming up to develop small molecules mimicking glial cell-derived neurotrophic factor (GDNF), a protein that helps nerve cells survive, for the treatment of Parkinson’s and other diseases. The collaboration builds on previous work by researchers at GeneCode, who together with Mart Saarma, PhD,…

Brain Neurotherapy Bio (BNB) has joined with Asklepios BioPharmaceutical (AskBio), a merger aiming to expand a gene therapy program for progressive neurodegenerative diseases such as Parkinson’s and multiple system atrophy (MSA), a form of atypical parkinsonism. “I’m pleased to welcome the Brain Neurotherapy Bio team to AskBio,” Sheila…

A new technique using tiny bubbles and ultrasound waves could ease the way for gene therapy to be delivered to the central nervous system, a mouse study suggests. The technique had a neuroprotective effect on mice, and those treated to model Parkinson’s showed improvements in measurements of motor function,…

Infusion of a naturally occurring protein, GDNF, into a motor control area of the brain may restore cells damaged by Parkinson’s disease and ease patients’ symptoms, results from a European clinical trial suggest. The study, “Extended Treatment with Glial Cell Line-Derived Neurotrophic Factor in Parkinson’s Disease” was published…

Administering a naturally occurring protein directly to the brains of rats increased the amount of the neurotransmitter dopamine going to the animals’ nerve cells, suggesting it could be a way to treat Parkinson’s, a study reports. The findings further demonstrate the MANF protein’s potential to treat Parkinson’s and other neurodegenerative disorders, according…

Recent research identified a new technology that can successfully deliver drugs across the blood-brain barrier, conferring neuroprotection in a mouse model of Parkinson’s disease. The study entitled “Heterotopic Mucosal Grafting Enables the Delivery of Therapeutic Neuropeptides Across the Blood Brain Barrier” was published in Neurosurgery…