UCB0599 reduces inflammation, improves coordination in mice

The experimental oral therapy UCB0599 — now in clinical trials — improves motor coordination and reduces inflammation and levels of the disease-related protein alpha-synuclein in a mouse model of Parkinson’s disease. “This comprehensive package of [Parkinson’s]-relevant improvements supports the rationale of directly targeting misfolded [alpha-synuclein] with the small molecule minzasolmin…

Mr. Motivator Marking World Parkinson’s Day With Fitness Class

To mark World Parkinson’s Day and underscore the importance of exercise for patients, the British fitness instructor known as “Mr. Motivator” is partnering with Parkinson’s UK. On April 13, the exercise guru will devote his weekly and half-hour, online Motivation Club class to Parkinson’s disease (PD), the organization announced.

How Playing Games Can Benefit People With Parkinson’s

We have become a screen society. Our days are often spent looking at screens rather than each other. I am no exception. There are digital versions of just about everything nowadays, including traditional board games. While apps can be convenient and beneficial, the feeling isn’t the same — using…

Interim Trial Data Hints at Efficacy of ANVS401

ANVS401, an investigational therapy for neurodegenerative diseases being developed by Annovis Bio, improved the speed and coordination of people with Parkinson’s disease in a Phase 2a clinical trial, an interim analysis suggests. “The results from this interim analysis are very encouraging. This brings us one step closer to…