A new case control study evaluated the association between caffeine consumption and risk of developing Parkinson’s disease (PD) in patients with high and low genetic susceptibility. The paper, entitled “Differential effect of caffeine intake in subjects with genetic susceptibility to Parkinson’s Disease,” was published in Scientific Reports. Parkinson’s disease,…
A recent published paper in Alzheimer’s & Dementia: the journal of the Alzheimer’s Association entitled “Improving the Clinical Detection of Lewy Body Dementia with the Lewy Body Composite Risk Score,” reports a new quick test to determine signs and symptoms of Lewy Body dementia…
Findings from a recent study published in the American Journal of Preventive Medicine revealed an association between increasing hours of television viewing per day and risk of death from its major causes in the United States, including Parkinson’s disease. TV viewing is the most prevalent of leisure-time behaviors…
University of Dundeen scientists have uncovered the molecular mechanisms and targets under the effect of a specific gene mutation involved in Parkinson’s disease development and which could prove to be strong targets for new therapies and even early disease detection. The paper entitled “Phosphoproteomic screening identifies Rab GTPases as novel downstream targets…
Recent research identified a new technology that can successfully deliver drugs across the blood-brain barrier, conferring neuroprotection in a mouse model of Parkinson’s disease. The study entitled “Heterotopic Mucosal Grafting Enables the Delivery of Therapeutic Neuropeptides Across the Blood Brain Barrier” was published in Neurosurgery…
In a recent paper published in The Lancet Neurology, researchers evaluated the analgesic effect of prolonged-release oxycodone-naloxone (OXN PR) in patients with Parkinson’s disease (PD) suffering from severe and chronic pain in a pioneer Phase II clinical trial. Pain is a very common, non-motory symptom in PD patients (approximately 60% of patients)…
Parkinson’s UK, the largest charity funder of Parkinson’s research in the U.K., recently launched a new research project that explores the possibility of using an individual’s skin odor to diagnose Parkinson’s disease. Watch the video below to learn more about this new project from Parkinson’s UK’s director of research, Arthur Roach:…
A team of researchers localized the specific types of neurons involved in movement, work that might be of relevance to understand neurodegenerative diseases like Parkinson’s and Huntington’s. The study, entitled “Cell-Type-Specific Sensorimotor Processing in Striatal Projection Neurons during Goal-Directed Behavior,” was published in Neuron. Neurodegeneration occurs when…
Researchers at King’s College London have identified a gene, HIFalpha, that plays a role in the regulation of nerve signals from damaged mitochondria that, in turn, affect nerve cell function, and which holds out the possibility of eventually finding a way to turn that gene off and restore function. The…
Researchers at the Georgetown University Medical Center reported nilotinib (Tasigna® by Novartis), a treatment for chronic myelogenous leukemia (CML), successfully treated Parkinson’s disease and Lewy body dementia patients in a Phase I trial. The complete results were presented during the annual meeting of the society of Neuroscience, Neuroscience 2015, held in Chicago…
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