Researchers at the Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo have uncovered a key protein, p53, as the key factor underlying the conversion from one cell type to another, such as skin cells to dopamine neurons. The research, which might have profound implications in the treatment…
News
In a recent study in the journal PLOS ONE, researchers from the Thomas Jefferson University demonstrate a way of helping the brain produce more of its own GM1 ganglioside, a molecule that has shown promise in relieving Parkinson’s symptoms and slowing disease progression. Numerous preclinical studies have shown that…
York University researchers have reported a new method of visual profiling that could help in the early detection of Parkinson’s disease. The study, titled “Classification of Parkinson’s Disease Genotypes in Drosophila Using Spatiotemporal Profiling of Vision,” was published in Scientific Reports. Parkinson’s is a disorder that affects motor…
Researchers at the Boyce Thompson Institute and Johns Hopkins University have discovered that salicylic acid, the primary product from aspirin breakdown, binds to and blocks an enzyme thought to play a major role in neurodegenerative diseases, including Parkinson’s disease. The research paper, titled “Human GAPDH Is a Target of Aspirin’s Primary…
The National Parkinson Foundation (NPF) announced that a proud milestone has been reached: it recently aided the 50,000th caller through its toll-free NPF Helpline. “NPF’s Helpline links our groundbreaking research to improve the lives of people with Parkinson’s today directly with the community we serve,” John Kozyak, the NPF’s Chairman of the…
Researchers have identified a specific protein involved in the functional upkeep of synaptic activity and detailed the process behind optimal neurotransmission — an activity whose breakdown is a defining feature of Parkinson’s and other neurodegenerative diseases. The research paper, entitled “Hsc70-4 Deforms Membranes to Promote Synaptic Protein Turnover by Endosomal Microautophagy” was published…
Exercise can be a powerful prescription for improving movement in Parkinson’s disease (PD) patients. Researchers, trying to pinpoint those exercises that might best quell PD symptoms, recently reported that both power training and yoga were helpful to older people with PD. Their study, titled “Comparative Impact of Power Training…
Scientists have identified a new strategy to attenuate one of the side effects — uncontrolled movement — caused by levodopa, the most effective treatment in the management of Parkinson’s disease symptoms. The study, entitled “M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced Dyskinesia,” was published…
Plant-produced flavonoids may help ward off Parkinson’s disease according to a new article from researchers in Malaysia and Australia. The report, titled “Protective Mechanisms of Flavonoids in Parkinson’s Disease,” appeared in the journal Oxidative Medicine and Cellular Longevity. Parkinson’s disease is a progressive neurological disorder in which dopamine cells…
Boston University School of Medicine and Northeastern University researchers have proposed a molecular mechanism by which only certain mutations in human apoA-1 protein cause familial amyloidosis while others do not. The research paper, entitled “Structural Stability and Local Dynamics in Disease-Causing Mutants of Human Apolipoprotein A-I: What Makes the…
Recent Posts
- MJFF grants totaling $7.6M will help Casma develop Parkinson’s therapy
- Planning is key when traveling with Parkinson’s disease
- I’m an optimist, but sometimes Parkinson’s fatigue is too much
- New smartphone platform helps doctors track Parkinson’s symptoms
- Camping can be a wonderful activity for those of us living with Parkinson’s