The rare lysosomal storage disorder Krabbe’s disease is caused by an enzyme deficiency and has been found to have surprising similarities with neurodegenerative disorders, including Parkinson’s disease. Establishing this connection can be a valuable tool for developing novel therapeutic targets and new biomarkers for identifying patients at risk for developing Parkinson’s.
A biomedical engineering professor from the University of Rhode Island (URI) is advancing the field of smart textiles to make Parkinson’s disease patients healthier and improve their quality of life. Kunal Mankodiya, who directs URI’s Wearable Biosensing Laboratory, is conducting research on ways to transform gloves, socks,…
The Michael J. Fox Foundation (MJFF) and Nike have so far raised $6.75 million for Parkinson’s disease research though their Nike Mag sneakers drawing and auctions this fall. The drawing and sales featured a limited-edition release of 88 pairs of the iconic Nike Mag self-lacing shoe. A final 89…
Researchers at the University of Alabama at Birmingham (UAB) were awarded a five-year $7.3 million grant from the National Institutes of Health (NIH) to evaluate new technology that could potentially improve outcomes from deep brain stimulation (DBS) in Parkinson’s disease patients. The research grant is part of the…
A new technology to deliver stem cell therapy to patients with neurological diseases such as Parkinson’s was developed by San Antonio scientists, according to a new study. The study, “MRI Guided Delivery of Neural Stem Cells into the Basal Ganglia of Nonhuman Primates Reveals a Pulsatile Mode of Cell…
CVT-301, an inhalable drug under development by Acorda Therapeutics to treat Parkinson’s symptoms during “off” periods when currently available drugs don’t adequately work, showed promising results in preclinical Phase 1 and 2 studies. Since the late 1960s, levodopa has been the most common and efficient oral drug used for managing Parkinson’s motor…
Growblox Sciences has filed the first of several likely patent applications for cannabis-based compounds developed by Growblox Life Sciences, its wholly owned subsidiary. The application applies to pharmaceutical-grade mixtures that might be used to treat patients with neurodegeneration, especially those with Parkinson’s disease. Growblox Life Sciences is focused on researching and developing cannabis-based medicines. The company uses various…
Researchers using a new system with real-time imaging to guide transplants of neurons into the brains of non-human primate models with Parkinson’s Disease not only allowed better oversight of the procedure, but also improved cell survival. The research report, “Real-Time Intraoperative MRI Intracerebral Delivery of Induced Pluripotent Stem Cell-Derived Neurons,” published in…
Treating Parkinson’s disease patients with high-frequency repetitive transcranial magnetic stimulation (rTMS) on both sides of the brain’s motor cortex improves bradykinesia (slow movement) and rigidity, according to a clinical trial analysis presented at the Fourth World Parkinson Congress, in Portland, Ore. The finding resulted from the analysis of a subset of patients from…
Researchers at Johns Hopkins University School of Medicine report their discovery that a protein called LAG3 acts as an enabler for a toxic natural aggregate to spread from cell to cell in the brains of mammals causing Parkinson’s disease development, and also of a means of blocking that protein’s…
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