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MRI Technique Helps Distinguish Between Parkinson’s and Progressive Supranuclear Palsy, Study Reports

A specific magnetic resonance imaging (MRI) measure can accurately predict the development of eye movement abnormalities, helping to identify patients who develop progressive supranuclear palsy with parkinsonism (PSP-P) after an initial diagnosis of Parkinson’s, a study shows. The study, “Refining initial diagnosis of Parkinson’s disease after follow‐up:…

L‐DOPA Treatment Prevents Age-related Iron Accumulation, Mouse Study Finds

Levodopa (L-DOPA) therapy is neuroprotective and prevents age-related iron accumulation in the substantia nigra, a brain region involved in Parkinson’s disease. The study with that finding, “L-DOPA modulates brain iron, dopaminergic neurodegeneration and motor dysfunction in iron overload and mutant alpha-synuclein mouse models of Parkinson’s disease,” was published in…

Agomelatine Worsens Motor Function, Neuron Loss in Parkinson’s Rat Study

A common depression treatment called agomelatine worsens Parkinson’s-related loss of dopamine-producing neurons, motor dysfunction, and protein oxidation, according to research in rats. The study with that finding, “Effects of Agomelatine in Rotenone-induced Parkinson’s Disease in Rats,” was published in the journal Neuroscience Letters. Neuroinflammation, oxidative…

Hypertension May Increase Risk of Parkinson’s, Study Reports

Patients with hypertension may be at a higher risk for Parkinson’s disease, according to a review of population-based studies. The review, “Association between Hypertension and the Risk of Parkinson’s Disease: A Meta-Analysis of Analytical Studies,” appeared in the journal Neuroepidemiology. Hypertension may cause damage…