Treatment with standard Parkinson’s therapies, such as levodopa or dopamine agonists, can provide effective relief of central parkinsonian pain, but they may fail to manage motor symptoms in these patients, a study has found. As many patients with Parkinson’s disease…
News
Abbott is partnering with the National Institutes of Health (NIH) to explore the use of its neuromodulation technologies for treating chronic pain and progressive movement disorders, including Parkinson’s disease. The partnership’s goal is to drive forward the Brain Research through Advancing Innovative Neurotechnologies initiative, known as…
PatientPoint, in collaboration with five U.S. patient advocacy organizations, has introduced a technology-driven point-of-care network for neurologists, neurology patients, and caregivers. With a focus on neurological conditions such as Parkinson’s and Alzheimer’s disease, the comprehensive network hopes to promote improved communication between patients and physicians. The new patient…
Lysosome-targeting Therapies Can Potentially Reverse LRRK2 Effects in Parkinson’s, Study Suggests
Mutations in the LRRK2 gene, which have been linked to familial Parkinson’s disease, impair the activity of the waste clearance system inside nervous brain cells, contributing to their progressive degeneration, a study finds. Using a compound called clioquinol, researchers could restore the activity of lysosomes — the…
Almost half of people in the early stages of Parkinson’s disease already have signs of neurodegeneration in a brain region called the caudate, which was previously thought to affect mostly those at advanced disease stages, a study reports. Early caudate involvement on both…
A two-year, global, observational study that will assess the contribution of genetic factors in the development of Parkinson’s disease has been launched by Centogene, in collaboration with the University of Lübeck. The new study (NCT03866603), which is called “Rostock International Parkinson’s Disease Study” or…
People who have appendectomies have more than three times the risk of developing Parkinson’s disease, according to the findings of a U.S. large-scale study. The study, “Parkinson’s Disease Is More Prevalent In Patients With Appendectomies: A National Population-Based Study,” will be presented during Digestive Disease Week (DDW) 2019,…
Neurologists treating patients with early-stage Parkinson’s disease should prescribe more often therapies that spare patients from starting levodopa too soon in order to delay onset of side effects associated with long-term use of the medicine, findings from a study conducted in Romania suggest. Researchers believe that even if a…
A new test can analyze cerebrospinal fluid samples and help measure how many toxic aggregates of alpha-synuclein can be found in the brains of patients with Parkinson’s disease. The new assessment strategy was developed by Japanese researchers and was reported in a study, “Ultrasonication-based rapid amplification of…
A wearable device called Personal KinetiGraph (PKG) can continuously and objectively monitor motor symptoms in people with Parkinson’s disease, which can help clinicians select the most appropriate management therapy and assess treatment impact, a study finds. The study, “Objective Data in Parkinson’s Disease: A Description of Over 27,000…
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