The experimental gene therapy AXO-Lenti-PD (OXB-102) was seen to be both safe and effective in a primate model of Parkinson’s disease, a study reported, supporting a clinical trial getting underway in patients. The findings were published in the journal Molecular Therapy Methods & Clinical Development in the paper, “…
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Aware that non-contact boxing routines can improve the lives of Parkinson’s patients, Senior Helpers is sending six Rock Steady Boxing (RSB) coaches to the organization’s national conference. Senior Helpers, a leading nationwide provider of at-home care, will sponsor the Wilmington, North Carolina, coaches in attending the second annual…
Bayer has announced an agreement to acquire the cell therapy company BlueRock Therapeutics, and plans to open a clinical trial of a potential Parkinson’s stem cell-based treatment this year. BlueRock, which will remain an independent entity under the plan, has a portfolio that focuses on engineered stem cell…
Neuroscientists have developed a simple and inexpensive way to measure tremors, one of the main symptoms of Parkinson’s disease, in lab mice using a smartphone. The new test showed comparable results to those generated with the expensive lab equipment currently used — opening a faster and more affordable way…
A scientist at the University of Sheffield in England has been awarded a £100,000 grant by Parkinson’s UK to develop a treatment that might slow or stop the progression of Parkinson’s disease and protect brain cells. The one-year grant, worth about $120,000, was given to Heather Mortiboys, a…
Alpha-synuclein in saliva may be a potential biomarker for Parkinson’s disease, according to a recent review article, but more research is necessary to determine its reliability as a possible screening approach. The study with that finding, “Salivary alpha‑synuclein as a biomarker for Parkinson’s disease: a systematic review,” was…
Alpha-arbutin — an antioxidant found in plants such as blueberry bush — may restore mitochondrial function in nerve cells and ease the motor disabilities associated with Parkinson’s disease, according to a preclinical study from China. Its results point to alpha-arbutin as a potential therapeutic compound for Parkinson’s and other…
Low vitamin D levels are associated with a greater tendency for falls, sleep problems, anxiety, and depression in people with Parkinson’s disease, according to a recent study. The findings, “Relationship between 25‐Hydroxyvitamin D, bone density, and Parkinson’s disease symptoms,” were published in the journal Acta…
Dopaminergic neurons — nerve cells gradually lost to Parkinson’s progression — that contain an enzyme called aldehyde dehydrogenase 1A1 are essential for acquiring the motor skills needed for proper movement in given situations, a mouse study reports. The research, “Distinct connectivity and functionality of aldehyde dehydrogenase 1A1-positive nigrostriatal dopaminergic…
Under-the-skin infusions of low-dose apomorphine using a wearable device called h-Patch may help in avoiding off periods and improving motor function in Parkinson’s patients, Valeritas, the technology’s developer, reports. A preclinical study found that apomorphine delivered using h-Patch could be detected in the blood within two hours, with a…
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