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Agomelatine Worsens Motor Function, Neuron Loss in Parkinson’s Rat Study

A common depression treatment called agomelatine worsens Parkinson’s-related loss of dopamine-producing neurons, motor dysfunction, and protein oxidation, according to research in rats. The study with that finding, “Effects of Agomelatine in Rotenone-induced Parkinson’s Disease in Rats,” was published in the journal Neuroscience Letters. Neuroinflammation, oxidative…

Hypertension May Increase Risk of Parkinson’s, Study Reports

Patients with hypertension may be at a higher risk for Parkinson’s disease, according to a review of population-based studies. The review, “Association between Hypertension and the Risk of Parkinson’s Disease: A Meta-Analysis of Analytical Studies,” appeared in the journal Neuroepidemiology. Hypertension may cause damage…

Study Highlights Importance of Personalized Parkinson’s Treatment

Invasive treatment approaches for advanced Parkinson’s disease have differential effects on disease-associated motor and non-motor symptoms, a real-life observational study shows. These findings suggest that selection of a treatment should be based on each patient’s particular clinical profile, researchers say. The study, “EuroInf 2: Subthalamic…

Treadmill Incline Training Improves Walking Speed of Parkinson’s Patients, Study Finds

Eight weeks of training on a treadmill with continuously varying surface inclines improved gait disturbances, particularly walking speed, in Parkinson’s disease patients, researchers report. Their finding were published in the study, “Exploring gait adaptations to perturbed and conventional treadmill training in Parkinson’s disease: Time-course, sustainability, and…

Monitoring with PKG System Helps Change Care in Nearly a Third of Parkinson’s Cases, Real-World Study Reports

Continuous monitoring of movement symptoms using a wearable device called the Personal KinetiGraph (PKG) may help clinicians make more appropriate treatment choices for their patients with Parkinson’s disease, according to a real-world clinical study. The study, “Qualitative Evaluation of the Personal KinetiGraphTM Movement Recording System in a…