Scientists have developed a new light-based deep brain stimulation method that when applied to neurons located in the subthalamic nucleus (STN) — a brain region involved in controlling movement — alleviated motor symptoms in a rat model of Parkinson’s disease. The study detailing that research, “…
Researchers have developed short gene promoters — structures that act like switches to turn on genes — that may boost the effectiveness of gene therapies targeting the central nervous system. These promoters allow for the delivery of larger genes into the central nervous system while keeping them active for…
The United States Food and Drug Administration (FDA) has granted breakthrough device designation to PhotoPharmics‘s light-based, at-home device as an add-on therapy for Parkinson’s disease. This designation is given to medical devices with the potential to offer more effective treatment for life-threatening or debilitating diseases. It grants…
Comparing the genomes of people with Parkinson’s disease to the specific genes expressed by cell types in the nervous system revealed an unexpected association between Parkinson’s and the digestive nervous system, according to a study. Another surprising result linked Parkinson’s to cells called oligodendrocytes, nervous system cells that…
Special bioelectronic devices that can be placed inside a person to diagnose, monitor, and treat neurological disorders, including Parkinson’s disease and epilepsy, may have taken a major step forward with the design of soft and flexible devices that are also biocompatible. Dion Khodagholy, PhD, assistant professor of…
Throughout the global COVID-19 pandemic, the Invertigo Dance Theatre will conduct its weekly Dancing Through Parkinson’s (DTP) classes online. Starting May 7, the Los Angeles, California-based company will offer free streaming classes live on Zoom each Thursday at 1:30 p.m. PST. The sessions will be recorded and available…
Encapsulating the antioxidant small molecule ellagic acid into a nanoparticle that also has some antioxidant properties may be a promising approach to treat neurodegenerative conditions, such as Parkinson’s disease, in which oxidative stress plays a critical role, a study suggests. In addition to reducing reactive oxygen species (ROS)…
To support the global Parkinson’s disease community during the COVID-19 pandemic, The Michael J. Fox Foundation (MJFF) is spotlighting its new information and resource hub. The dedicated site includes webinars, podcasts, online educational events, insights and tips regarding PD and the coronavirus, and a virtual…
A new tool, based on multiple signs of disease progression, can help guide healthcare professionals in decisions on when to start palliative care for people with Parkinson’s, researchers report. Their study,”RADPAC-PD: A tool to support healthcare professionals in timely identifying palliative care needs of people with…
Investigational therapy ANVS401 (also known as Posiphen) reversed gastrointestinal dysfunction linked to early Parkinson’s in two mouse models of the disease. Results of the study, “Translational inhibition of α-synuclein by Posiphen normalizes distal colon motility in transgenic Parkinson mice,” were published in…
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