News

Sunovion‘s Kynmobi (apomorphine hydrochloride), a sublingual film treatment for “off” episodes in people with Parkinson’s disease, has a manageable safety profile and maintains efficacy over up to nearly a year of use, interim data from an ongoing Phase 3 trial show. Findings were presented at MDS…

Mutations in the PARK7 gene, known to cause early onset Parkinson’s disease, result in low levels of a protein called DJ-1 that is essential for nerve cell health, a study revealed. In fixing a protein processing malfunction in cells derived from members of…

Vercise Genus, a fourth-generation system for deep brain stimulation (DBS) made by Boston Scientific, has received CE marking and is now commercially available in Europe. A treatment approach for Parkinson’s disease, DBS involves surgically implanting a neurostimulator to deliver electrical impulses to targeted regions of…

Disturbed sleep, like that due to sleep apnea, significantly associates with poorer cognition in Parkinson’s disease patients, particularly in the domains of attention, executive function, and memory, a study reported. The study, “Sleep Disturbances and Sleep Disordered Breathing Impair Cognitive Performance in Parkinson’s Disease,” was published…

Hidrox, a compound extracted from olives, can significantly ease Parkinson’s motor symptoms, reduce alpha synuclein buildup, and slow neurodegeneration in animal models of the disease, a recent study has found. Though Hidrox is known mostly for its antioxidant effects, its benefits in Parkinson’s went beyond a decline…

D&D Pharmatech has launched a new company called Valted Seq, aimed at discovering pathways and biomarkers relevant to neurodegenerative diseases such as Parkinson’s. To this end, the company claims in a press release to have created the world’s largest repository of single-cell sequencing data. This data comes…

Astrocytes, the star-shaped cells that provide physical support for neurons in the brain, also appear to contribute to the development and progression of Parkinson’s disease, a recent study suggests. Compared with healthy astrocytes, those containing Parkinson’s mutations showed multiple hallmarks of the disease, including the presence of…

A partnership between Kizik and the Parkinson’s Foundation aims to make the company’s hands-free shoes more available to Parkinson’s patients. The collaboration includes a Kizik donation of an unspecified amount to the nonprofit organization. And it is in keeping with the foundation’s goal of making life better for …

The levels of monocyte chemoattractant protein 1 or MCP-1 — a molecule that helps guide certain types of immune cells to inflammation sites — in the cerebrospinal fluid are associated with disease progression in people with Parkinson’s, a study shows. But the MCP-1 levels in the clear fluid…

A high-resolution 3D model of the leucine-rich repeat kinase 2 (LRRK2) protein provides some hints as to how this molecule participates in Parkinson’s disease — and suggests ways to sidestep its abnormal behavior, a new study reported. In its active form, LRRK2 binds to structures of the cell’s…