A considerable amount of effort is being put into finding therapeutic agents for Parkinson’s disease, with several symptomatic and disease-modifying therapies currently being evaluated in clinical trials, according to a recent comprehensive review. The review, “Parkinson’s Disease Drug Therapies in the Clinical Trial Pipeline: 2020,” was…
Remote coaching via telehealth could help people with Parkinson’s disease stay physically active, even when in-person events aren’t feasible, a study suggests. The study, “Promoting Physical Activity via Telehealth in People With Parkinson Disease: The Path Forward After the COVID-19 Pandemic?” was published in Physical Therapy.
Inhaled bacterial toxins can cause inflammation in a brain region associated with smell, and this inflammation may help in the initiation and propagation of Parkinson’s-related molecular changes in the brain, a study in mice suggests. The study, “IL‐1β/IL‐1R1 Signaling Induced by Intranasal Lipopolysaccharide Infusion Regulates Alpha‐Synuclein…
People who had a concussion are more likely to be diagnosed later in life with Parkinson’s disease and other neurologic disorders than those who never had this type of brain injury, a database study reports. The study, “Associations between concussion and risk of diagnosis of psychological…
Tinnitus, a sensation of sound without any source, appears to precede Parkinson’s and Alzheimer’s diseases and may serve as a sign of increased risk for those conditions, according to a recent study. The study, “Tinnitus and risk of Alzheimer’s and Parkinson’s disease: a retrospective nationwide…
The Michael J. Fox Foundation (MJFF) has awarded a total of $8.5 million to research teams at AC Immune, Mass General Brigham, and Merck to develop a way to detect the protein alpha-synuclein in the brains of people living with Parkinson’s disease. The three…
Parkinson’s UK is asking patients and others in the community to take part in a survey about research participation in the wake of the COVID-19 pandemic, and possible adaptations for study environments. The goal is to help researchers make sure that face-to-face studies restart in ways that are safe,…
AC Immune anticipates advancing ACI-12589, its novel alpha-synuclein positron emission tomography (PET) tracer for Parkinson’s disease diagnosis, to clinical development in the last quarter of this year. Based on positive new data, the company made the announcement during an oral presentation at the virtual Alzheimer’s Association International…
Axial Biotherapeutics announced a $440,000 grant from the Michael J. Fox Foundation for Parkinson’s Research to support its efforts to develop a model that can mimic the nervous system of the gastrointestinal tract, and help in evaluating potential Parkinson’s disease treatments. Though Parkinson’s is primarily considered a neurodegenerative disorder,…
The levels of two types of fatty molecules — anandamide and glucocerebroside — are significantly altered in people with Parkinson’s disease, and associate with sensory nerve damage and chronic pain, a study reported. These findings suggest that patients with sensory problems and pain may benefit from available…
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