The Michael J. Fox Foundation for Parkinson’s Research (MJFF) has awarded a $5 million grant to Congruence Therapeutics to advance the development of small molecules for Parkinson’s disease associated with mutations in the GBA1 gene. The research grant will support the optimization and clinical development of therapeutic candidates…
Scientists at the University of Rochester have developed an artificial intelligence (AI)-powered screening tool that analyzes a person’s speech patterns to detect subtle signs of Parkinson’s disease. The algorithm could eventually be used to analyze speech patterns at home on mobile phones or household devices, helping to reach people…
A five-year, $3.4 million grant from the National Institute of Environmental Health Sciences is supporting research into how manganese exposure may increase the risk of developing Parkinson’s disease. Manganese is an essential mineral the body needs in small amounts. However, high-level exposure, such as through certain pesticides, mining, or…
Prescribing medication for Parkinson’s disease is not straightforward, but instead is influenced by a wide range of factors and behavioral drivers, according to a new study from Europe that investigated possible reasons for the choices of prescription drugs given by treating clinicians. Beyond clinical guidelines, the researchers found that…
S.Biomedics said its stem cell-based therapy A9-DPC was found safe and effective in improving motor function over a one-year follow-up in people with Parkinson’s disease. The results apply to all 12 adults diagnosed with Parkinson’s for at least five years, who were treated with a single brain transplant…
Health Canada will review Knight Therapeutics’ application seeking approval of Crexont, an extended-release formulation of levodopa and carbidopa aimed at providing steady symptom control in Parkinson’s disease, the company said. The Parkinson’s therapy is designed to maintain consistent levels of levodopa and carbidopa in the body, prolonging…
Two trained dogs detected Parkinson’s disease with high accuracy by smelling skin swabs of patients who had not yet received treatment, adding to growing evidence that scent carries a chemical signature that could help enable early, noninvasive diagnosis. Bumper, a golden retriever, and Peanut, a black Labrador, were trained…
A weekly injectable implant could make treatment for Parkinson’s disease easier and more effective by steadily releasing levodopa and carbidopa into the bloodstream and replacing the need to take the medications multiple times a day, according to a study led by the University of South Australia (UniSA). “Our…
A research grant from The Michael J. Fox Foundation for Parkinson’s Research (MJFF) will support a new study that’s investigating the biological mechanisms underlying anxiety as a symptom of Parkinson’s disease. Titled “Investigating the Mechanisms of Alpha-synuclein-induced Anxiety in a Novel Preclinical Model of Parkinson’s Disease,” the…
Neuraxpharm is partnering with Dizlin Pharmaceuticals on Dizlin’s Infudopa SubC drug-device combination therapy, which allows for continuous levodopa-carbidopa delivery in people with advanced Parkinson’s disease. Infudopa SubC is a wearable device being developed for patients who experience fluctuations in their Parkinson’s motor symptoms despite treatment. “Our…
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