A smartphone application designed to measure and monitor the walking mobility of people with Parkinson’s disease captured a 44% decrease in daily activities during the COVID-19 pandemic lockdowns, a study assessing the app reported. The lack of movement was due to confinement, not worsening disability, the…
Treatment with the antioxidant metal-alloy nanozyme reduced the build-up (aggregation) and transmission of disease-causing alpha-synuclein protein in the nerve cells and brains of a Parkinson’s disease mouse model, a study reported. Investigators believe these findings support further research to evaluate nanozymes as a Parkinson’s treatment.
Changes in how brainwaves synchronize, known to occur in people with Parkinson’s disease, originate from distinct nerve cell networks in multiple brain regions involved in motor control, a study found. Applying electrical stimulation to correct the abnormally coupled brainwaves may benefit…
Visual hallucinations in people with Parkinson’s disease are associated with a thinning of the inner layers of the eye’s retina, an exploratory study reported. Published in the journal Nature Scientific Reports, the study was titled “…
Production of the protein TOM20 rescued nerve cells that are damaged in people with Parkinson’s disease due to the toxic buildup of alpha-synuclein protein, a study in rats revealed. According to researchers, the interaction between TOM20 and alpha-synuclein represents a potential…
Scientists have created a tomato enriched in levodopa, or L-DOPA, a standard therapy for people with Parkinson’s disease. These tomatoes could represent a scalable, low-cost alternative L-DOPA source for Parkinson’s patients, particularly those in developing nations where treatment cost is prohibitive.
Using non-invasive, dry-electroencephalography (EEG) and machine-learning computer algorithms, researchers were able to distinguish between Parkinson’s disease patients with and without mild cognitive impairments with 80% accuracy, early results of a study found. Follow-up assessments will be…
Scientists have designed a so-called “organ-on-a-chip” device that can grow dopaminergic neurons — the brain cells most affected in people with Parkinson’s disease — in a 3D environment where they are more like real neurons in the brain, a study shows.
Scientists at the University of Copenhagen (UCPH) in Denmark have developed an artificial intelligence (AI) tool to monitor and track the dynamics of protein movement and function, which can advance the understanding behind neurodegenerative disorders such as…
Constipation and sleep behavior disorder are strongly associated with future decline in some cognitive measures in people — especially men — newly diagnosed with Parkinson’s disease, a study suggested. Its researchers recommend early assessment of sleep disorders and constipation to help predict cognitive changes in later disease stages. …
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