Marisa Wexler, MS,  senior science writer—

People with Parkinson’s disease who have clinically significant anxiety tend to walk more slowly and with shorter steps than people with the disease who don’t have anxiety. That’s according to the study, “The impact of anxiety on gait impairments in Parkinson’s disease: insights from sensor-based gait analysis,” which…

Variations in genes that are important for the function of lysosomes — the cellular equivalent of garbage disposals, which are responsible for removing molecular waste from cells — may help set the stage for the development of Parkinson’s disease in people who’ve had long-term pesticide exposure, a new study…

Self-care is important for people with Parkinson’s disease, and patients should be armed with tools for tracking symptoms, keeping informed about the disease, and leaning on support from others. That’s according to a study, “Balancing feeling ‘prepared’ without feeling ‘devoured’: A qualitative study of self-care from…

ND0612, a formation of levodopa/carbidopa administered continuously by an under-the-skin pump, led to better symptom control for people with advanced Parkinson’s disease in a Phase 3 trial, and the therapy’s efficacy and safety were consistent irrespective of patient factors like age, weight, and medication dosage. That’s according to…

Treatment with prasinezumab — an experimental therapy designed to stop toxic alpha-synuclein protein clumps from spreading through the brain — seems to slow the progression of motor symptoms in people with Parkinson’s disease. That’s according to the results of a new analysis that compared the findings of a…

The Syn-One test, which uses a skin biopsy to look for atypical clumps of the protein alpha-synuclein, may help both in confirming a diagnosis and guiding treatment decisions for people being evaluated for Parkinson’s disease, new data show. “Skin biopsies are minimally invasive and, our study showed, very effective…

AB-1005, an experimental gene therapy administered directly into the brain, helped ease motor symptoms in patients with moderate Parkinson’s disease, whereas it appeared to stabilize disease progression for those with mild disease in a small Phase 1 clinical trial. No serious safety issues were reported for the 11…

A new treatment that delivers healthy mitochondria to damaged nerve cells showed promise in cell and animal models of Parkinson’s disease, a study shows. “[T]he study findings provide evidence that mitochondria transplantation can be developed as a novel therapeutic for” Parkinson’s, researchers wrote in “Mitochondrial transplantation…

A new machine learning model is able to identify Parkinson’s disease more accurately than other models based on electroencephalography (EEG) readings of the brain’s electrical activity, a study found. “The proposed model holds promising potential as a valuable and enduring aid for experts and clinicians in diagnosing” Parkinson’s, researchers…

Anxiety is common among people with Parkinson’s disease and contributes to a worse life quality for patients irrespective of motor symptom severity, according to a new German study. Nearly 40% of the patients in the small study were found to have clinically relevant anxiety — and those with more…