Author Archives: Marisa Wexler

New Rasagiline Formulation May Allow Application to Skin

A new formulation of rasagiline, approved for Parkinson’s disease, may allow the therapy to be given by applying it to the skin. The treatment’s new formulation was described in the European Journal of Pharmaceutics and Biopharmaceutics, in a study titled “Microemulsion-based gel for the…

Salivary Caffeine Levels Decreased in Some Patients

People with moderate or advanced Parkinson’s disease have abnormally low levels of caffeine in their saliva, despite normal caffeine metabolism, a new study indicates. The findings suggest that measuring caffeine in saliva could be useful for gauging Parkinson’s disease progression. The study, “Salivary caffeine in Parkinson’s…

Study Uncovers Genetic Variants Linked to Disease Progression

Scientists have identified genetic variations that are associated with different rates of disease progression in people with Parkinson’s disease. The findings suggest that the genetic changes that affect disease progression are distinct from those that impact whether a person will get Parkinson’s at all, and that disease initiation and…

Neurons, Not Nearby Cells, Decide Dopamine Levels, Study Reports

Dopamine-releasing cells in the brain, much like most other hormone-producing cells, have a self-regulating feedback mechanism that controls their activity, researchers have discovered. That is, healthy nerve cells themselves determine how much dopamine will be released, the research team found, in contrast with the prevailing view that nearby cells “control”…

Ways of Better Ensuring Good Dental Care in Parkinson’s Reviewed

Regular dental visits and routine tooth brushing with alternating hands are among recommendations for better oral health in people with Parkinson’s disease, researchers report. Tooth decay and receding gums are known problems for these patients, and often overlooked due to the nature of this neurodegenerative disorder, the team noted. The paper,…

Parkinson’s Mutation Causes Impaired Neuron Growth Throughout Life

Dopamine-producing neurons in the brain grow throughout life, but this growth is hindered by a genetic mutation that is associated with the development of Parkinson’s disease, a new study demonstrates. The researchers hope these findings will lead scientists to “focus on enhancing the generation of new dopamine-producing neurons, rather…

Research Sheds Light on Iron Accumulation in Patients’ Brains

In Parkinson’s disease, iron accumulates in certain parts of the brain that have characteristic genetic profiles, according to a new study. This finding may help to explain the biological processes that cause Parkinson’s, which could be important for developing treatments. The study, “Regional brain iron…

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