People with sporadic Parkinson’s disease and those with Parkinson’s-associated mutations in the GBA gene show a distinct immune cell profile in the blood relative to healthy people, a study showed. In turn, Parkinson’s patients carrying disease-causing LRRK2 mutations had an immune cell profile comparable to people without any disease.
People with Parkinson’s disease are more likely to report a good quality of life if their caregivers are not strained, a new study suggests. “As caregiver strain was found to be related to patients’ QoL [quality of life], improvement in QoL for PD [Parkinson’s disease] patients may hinge on…
Shirley Ryan AbilityLab, a rehabilitation center located in Chicago, Illinois, will conduct a study that will use Datos Health‘s remote care platform Open Care to monitor physical activity in people with Parkinson’s disease and other neurological disorders. “The research study will allow us to determine the feasibility…
Nervtex’s MoDAS artificial intelligence (AI) system has become the first video-based, AI-powered medical device to win regulatory approval for assessing motor symptoms in Parkinson’s disease and other movement disorders, according to a company press release. The AI system, which analyzes motor symptoms based on video recorded on a…
ATH434, Alterity Therapeutics’ experimental oral therapy, prevented a loss in the sense of smell — an early and common symptom of Parkinson’s disease — in a mouse model, and helped to preserve nerve cells and restore motor skills in older animals, a study showed. These findings add to those…
The activity of multiple genes in the brain varies according to sex among people with Parkinson’s disease, a new study reports. These differences may contribute to discrepancies in how Parkinson’s tends to affect men and women. “While males have a higher age-adjusted disease incidence and are more frequently affected…
Suppressing the production of an enzyme called nitric oxide synthase 2 (NOS2) led to reductions in alpha-synuclein-related abnormalities and neuroinflammation in a mouse model of Parkinson’s disease, a new study reports. “Our data indicate that NOS2 may be a therapeutic target for modulating [Parkinson’s disease] in the brain,” the…
The U.S. Food and Drug Administration (FDA) has lifted its full clinical hold on IkT-148009, Inhibikase Therapeutics’ investigational oral therapy for Parkinson’s disease. The agency had placed a hold on all clinical trials of IkT-158009 in December, just a few months after Inhibikase had begun dosing Parkinson’s patients in a …
The PD GENEration study is halfway to its goal of providing free genetic testing and counseling to 15,000 people with Parkinson’s disease, with 7,500 patients included in the effort to date. “Ensuring that the entire Parkinson’s community — including the 90,000 individuals expected to receive a PD [Parkinson’s…
A cognitive-motor training program featuring a video game platform that promotes exercise is feasible for people with Parkinson’s disease to use, a new study demonstrates. Patients using the program along with standard rehabilitation showed comparable and greater motor and cognitive improvements relative to those on standard rehabilitation alone. These preliminary…
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