Celon’s small molecule eases levodopa-induced dyskinesia
A daily dose of CPL’36, an oral small molecule in the pipeline of Celon Pharma, may ease symptoms for patients…
Articles by Margarida Maia, PhD
Combined DBS approach found safe, feasible in Parkinson’s
Inserting a piece of nerve tissue from a patient’s ankle into the brain during deep brain stimulation (DBS) surgery appears…
Immune responses may explain Parkinson’s sex-specific differences
Men with Parkinson’s disease mount stronger and more frequent immune responses than do women against PINK1, a protein that…
13 blood biomarkers may aid in diagnosing Parkinson’s, study says
Thirteen blood biomarkers, including three never previously linked to Parkinson’s disease, may help in diagnosing people sooner and scientists…
Cholesterol byproduct may be therapeutic target for Parkinson’s
A compound formed by nerve cells as they break down cholesterol appears to be involved in the formation of toxic…
Study offers insight into how sex differences affect Parkinson’s
Male and female mice show different responses to toxic alpha-synuclein clumps, a hallmark of Parkinson’s disease, with males experiencing…
Molecular switch for toxic protein disposal may be Parkinson’s target
A global team of researchers has identified the molecular switch in a protein complex that regulates how cellular waste disposal…
Adaptive DBS may move to pivotal clinical trial after $14M raised
Newronika plans to use the 13.6 million euros (about $14.3 million) raised in a funding round to support what…
Alpha-synuclein clumps may form in kidneys before traveling to brain
People with chronic kidney disease, a condition characterized by a progressive loss of kidney function, have alpha-synuclein protein deposits in…
84% of people with Parkinson’s report sleep problems in study
A large proportion of people with Parkinson’s disease struggle with sleep problems, including issues with falling asleep or maintaining…