The National Institutes of Health (NIH) has awarded Sinopia Biosciences $3.3 million to advance the development of its small molecule candidate for Parkinson’s disease. Sinopia will use the grant to move the small molecule forward through investigational new drug (IND)-enabling studies. An IND is a medicine that has…
Tracking blood pressure with a smartwatch could help people with Parkinson’s disease manage the sudden drop in blood pressure — called orthostatic hypotension — that can occur when changing positions, according to a study by researchers at the Samsung Medical Center, in South Korea. Measurements obtained with Samsung’s…
A walking program seems to boost the benefits of respiratory muscle training — which consists of specific exercises designed to improve the function of muscles used in breathing — in people with Parkinson’s disease, a small study has found. In the study, patients who followed an eight-week walking program…
The Silverstein Foundation for Parkinson’s with GBA is supporting early work by AcureX Therapeutics to bring into patient testing potential disease-modifying treatments for Parkinson’s disease. Specifically, grant funding will go to advance the development of small molecule compounds targeting the path involving a specific protein in mitochondria — the…
Bial has entered into an exclusive agreement to market upon approval in Europe APL-130277 — Sunovion Pharmaceuticals‘ sublingual (under the tongue) film of apomorphine for off episodes in Parkinson’s disease. Under the agreement’s terms, Bial will be responsible for preparing a marketing authorization application for regulatory agencies there — drawing on…
A $200,000 gift from the Cargill family will help to support studies into gait that is affected by Parkinson’s disease. The money, from the estate of Bob and Sara Lou Cargill and given by their daughter Sara Beth Lee and her husband John Lee, who has Parkinson’s, will go toward…
Transcranial stimulation — a noninvasive procedure that sends low-level electric currents to certain brain regions — may boost the benefits of aerobic exercise and improve gait for people with idiopathic Parkinson’s disease, a small study reports. “We found that transcranial stimulation activated the pre-frontal cortex, a brain region that Parkinson’s…
Shape Therapeutics and Roche have entered into a strategic collaboration and license agreement to develop RNA-based gene therapies for Parkinson’s, Alzheimer’s, and rare diseases. Under the terms of the agreement, Shape will use its proprietary RNA technologies to leverage molecular machinery already present in human cells to…
Patient dosing has been completed in the Phase 2a clinical trial testing ANVS401, Annovis Bio’s investigational therapy for Alzheimer’s disease and Parkinson’s disease. An additional 40 patients with Parkinson’s disease were treated with ANVS401, with the company now preparing to share final safety and efficacy data later this year. According to…
A new hydrogel matrix appears to ease the delivery of therapeutic stem cells into the brain, a necessary step in potentially using these cells to treat Parkinson’s disease. In animal models, this hydrogel was found to provide a safe scaffold for stem cells to differentiate into dopamine-producing nerve cells —…
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