VQ-101, targeting GBA gene mutations, to enter clinical testing
Vanqua Bio will initiate clinical development of VQ-101 — a small molecule capable of penetrating the brain — in…
Articles by Margarida Maia, PhD
Low-dose fosgonimeton boosts cognition in dementia patients: Trial
Low-dose fosgonimeton (ATH-1017), an investigational small molecule, may have cognitive benefits for people with Parkinson’s disease-related dementia or dementia…
Cutting fossil fuels may save 5.1M lives per year, study finds
Phasing out fossil fuels could save an estimated 5.1 million lives each year worldwide by preventing deaths attributed to ambient…
Better health literacy tied to healthier exercise habits in survey
People with Parkinson’s disease who maintain the recommended level of weekly physical activity tend to be those with critical…
Examining skin cells may aid in early Parkinson’s diagnosis
Some molecular changes that drive damage to brain cells in Parkinson’s disease take place in skin cells too, a…
Trial of AAV-GAD gene therapy to be fully enrolled by end of year
A Phase 1/2 clinical trial testing AAV-GAD, an investigational gene therapy being developed by MeiraGTx for Parkinson’s disease,…
Heart PET scans help to spot Parkinson’s years before symptoms
Positron emission tomography (PET) scans of the heart can help to identify people, known to be at risk for…
MTX325 shows promise in mouse model as Parkinson’s therapy
Mission Therapeutics’ experimental oral therapy MTX325, for Parkinson’s disease, spurred brain cells in mice to clear damaged mitochondria…
Alpha-synuclein clumps may lead to calcium imbalance in Parkinson’s
Toxic clumping of the alpha-synuclein protein, a hallmark of Parkinson’s disease, may lead to a calcium imbalance in which…
DBS offers lasting motor benefits in GBA-associated Parkinson’s
For people with Parkinson’s disease associated with mutations in the GBA gene, deep brain stimulation (DBS) may offer lasting…