SHLP2 mutation halves the odds of developing Parkinson’s
People who carry a specific mutation in the gene for a small protein called SHLP2 are about half as likely…
Articles by Margarida Maia, PhD
How proteins LRRK2, Rab29 work together to drive Parkinson’s: Study
Scientists have uncovered the complex structure and interplay of two proteins, called LRRK2 and Rab29, that are implicated in late-onset…
Cycling tour of Canada ‘profoundly’ eased man’s Parkinson’s symptoms
A man with Parkinson’s disease saw an easing of his motor and nonmotor symptoms and better fitness after taking…
NEMO protein crucial for clearing nerve cells of toxic alpha-synuclein
A protein called NEMO can dock to misfolded forms of alpha-synuclein — the protein whose toxic aggregates damage and kill…
Alpha-synuclein prods neurons’ protein gain, causing them to die
Alpha-synuclein, the protein that builds up into toxic clumps in Parkinson’s disease, may trigger neurons (nerve cells) to increase…
Avoiding toxins, head injury key to Parkinson’s prevention, study says
Factors such as exposure to environmental toxins and repeated blows to the head — all of which can be reduced…
Alpha-synuclein clumps may travel via vagus nerve from gut to brain
Alpha-synuclein — the protein that forms toxic clumps in the brains of people with Parkinson’s disease — may travel…
Ceramic blanket improves motor performance in Parkinson’s mice
A ceramic blanket, a device being developed by Gladiator Therapeutics to improve blood flow and speed up wound healing,…
VQ-101, targeting GBA gene mutations, to enter clinical testing
Vanqua Bio will initiate clinical development of VQ-101 — a small molecule capable of penetrating the brain — in…
Low-dose fosgonimeton boosts cognition in dementia patients: Trial
Low-dose fosgonimeton (ATH-1017), an investigational small molecule, may have cognitive benefits for people with Parkinson’s disease-related dementia or dementia…