Enrollment Complete in Phase 2 Trial of Possible Therapy NYX-458
Enrollment is now complete for a Phase 2 trial of NYX-458, Aptinyx’s investigational therapy to treat cognitive impairment in…
Articles by Lindsey Shapiro, PhD
PPARGC1A Gene Variants May Be Linked To Some Parkinson’s Types
Patients with early-onset or familial forms of Parkinson’s disease (PD) had a higher burden of rare mutations in the…
Sleep Problems in Parkinson’s May Be Linked to Certain Medications
Sleep disturbances are common in people with diseases marked by alpha-synuclein buildup, but they are especially problematic among Parkinson’s…
Exercise Eases Motor Symptoms in Parkinson’s Early-to-mid Stages
At least six months of physical therapy helps to ease motor symptoms, possibly allowing for lower medication doses among people…
Weight Loss Over 5 Years Linked to Faster Parkinson’s Progression
Fluctuations in weight, either a loss or a gain, occurred significantly more often in people with Parkinson’s disease than…
Researchers Design New Approach to Help Medications Enter the Brain
Researchers have developed a new method of temporarily opening the selective blood-brain barrier (BBB) to allow therapeutic molecules greater access…
Buntanetap Shows Efficacy, Supports Soon-to-open Phase 3 Study
Buntanetap, Annovis Bio’s investigational oral treatment for neurodegenerative diseases, was safe and showed effectiveness in people with early-stage Parkinson’s…
Glycosphingolipid Levels Altered in Blood of Parkinson’s Patients: Study
Multiple alterations to a class of fat (lipid) molecules called glycosphingolipids (GSLs) are observed in the blood of people with…
More, Worse Parkinson’s Pain for Women Than Men, Study Reveals
Women with Parkinson’s disease experience more and worse pain than men with the neurodegenerative condition, according to a new…
Stigma of Parkinson’s Influenced by Other Conditions
More co-existing health conditions in people with Parkinson’s disease is associated with a greater self-perception of stigma and a lower…