Study Links Smoking, Reduced Parkinson’s Risk, But Comes with Caveat
Smoking more cigarettes or for a longer time is associated with a decreased risk of developing Parkinson’s, according to…
Articles by José Lopes, PhD
PF-06412562 Safe, Eases Motor Impairments in Parkinson’s Patients, Phase 1 Trial Finds
A compound that targets two specific dopamine receptors in the brain is safe and can ease motor deficits in Parkinson’s…
Study Outlines Risk Factors for Levodopa-induced Dyskinesia in Newly Diagnosed PD Patients
Severe motor, functional, and gait impairment; cumulative levodopa exposure; anxiety, and sex are among the risk factors for developing levodopa-induced…
Design, Development of BeatHealth System for Parkinson’s Gait Impairments Described in Study
Researchers have developed a system — a mobile app and two websites — based on musical stimuli to improve gait…
For First Time, Precursors of Dopamine Neurons Implanted in Brain of Parkinson’s Patient
Precursors of dopamine-producing cells were implanted into the brain of a Parkinson’s patient for the first time. The patient…
Personalized Tissue Implants From Patients’ Own Cells Have Potential to Treat Parkinson’s, Study Suggests
A new, fully personalized tissue implant using a patient’s own materials and cells can regenerate any organ in the body…
Dopamine Depletion Not Associated with Non-motor Symptoms in Key Parkinson’s Brain Area, Study Shows
Dopamine depletion in a brain region called the striatum does not correlate with the severity of non-motor symptoms in…
Inflammation-related Protein Complex a Potential Therapy Target for Parkinson’s, Study Says
Oral administration of a small molecule specifically blocked the activation of a stress-sensing protein complex called the NLRP3 inflammasome and prevented the…
Parkinson’s Patients Without Cognitive Impairment Have Normal Life Expectancy, Study Suggests
While patients with some types of parkinsonism have a shorter lifespan, those with Parkinson’s disease without cognitive impairment have a…
Alpha-Synuclein Could Be Biomarker for Non-Motor Symptoms in Parkinson’s, Study Suggests
Reduced alpha-synuclein levels in the cerebrospinal fluid (CSF) — the liquid surrounding the brain and spinal cord — are associated…