Spinal Cord Stimulation Fails to Improve Mobility in Advanced Parkinson’s Patients
Despite being safe, spinal cord stimulation does not lead to significant improvements in mobility in patients with advanced…
Articles by Joana Carvalho, PhD
New Device Measures Levels of Pro-inflammatory Cytokines Found in Parkinson’s Patients
Scientists have created a device that allows them to accurately measure the levels of different pro-inflammatory cytokines — molecules…
Duloxetine in Trial Fails to Ease Pain, But May Help with Motor Skills
Use of duloxetine, a treatment for depression and nerve pain, fails to alleviate pain in people with Parkinson’s…
Mutations in ATP10B Gene May Increase Risk of Parkinson’s, Study Finds
Mutations in a gene called ATP10B may increase the risk of developing Parkinson’s…
Rare Variants in Lysosomal Genes Linked to Parkinson’s, Study Finds
Scientists have discovered a series of rare variants in genes that control the function of lysosomes — cell compartments…
Probiotic Strain of B. Subtilis Halts Alpha-synuclein Aggregation in Round Worms
A probiotic strain of the bacteria Bacillus subtilis called PXN21 can prevent the buildup of the protein alpha-synuclein…
Foliglurax Fails to Minimize Long-term Use Side Effects of Levodopa, Phase 2 Trial Shows
Despite being safe and well-tolerated, foliglurax (PTX002331), an investigational therapy for Parkinson’s disease, failed to significantly reduce some…
Activated Immune T-Cells Infiltrate the Brain and Promote Neurodegeneration in Primate Models of Parkinson’s
Activated immune T-cells can infiltrate the brain and promote neurodegeneration in non-human primate models of Parkinson’s during the chronic stages…
Potential Oral Treatment Shows Promise in Early Study in Volunteers, Neuropore Says
A potential oral therapy for Parkinson’s disease and amyotrophic lateral sclerosis (ALS) was seen to be…
Cancer Medication Tasigna Safely Boosts Dopamine Levels in Brain of Parkinson’s Patients, Phase 2 Trial Shows
Tasigna (nilotinib), an approved leukemia medication being tested as a repurposed treatment for Parkinson’s disease, was found to…