Author Archives: Joana Carvalho

Alpha-Synuclein Impairs ClpP Enzyme, Causing Mitochondrial Damage, Study Says

Alpha-synuclein reduces the levels and impairs the function of ATP-dependent Clp protease (ClpP), an enzyme found in mitochondria — the cell compartments responsible for the production of energy — causing mitochondrial damage and oxidative stress, a study shows. The study, “Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative…

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