Andrea Lobo,  —

The American Parkinson Disease Association (APDA) has announced that it will host its third annual, free, virtual conference for people with Parkinson’s disease and their caregivers on Feb. 19-20. The program is scheduled to run from 12 p.m. to 4 p.m. ET each day. Tailored to “educate, empower…

Treatment with Vyalev (foscarbidopa and foslevodopa) eased motor symptoms and sleep disturbances in a 50-year-old man with Parkinson’s disease and a history of dream enactment behavior, according to a case report from Japan. Dream enactment behavior is a sign of rapid eye movement (REM) sleep disorder, in which…

People with neurodegenerative diseases like Parkinson’s disease or dementia are more vulnerable to heat-related complications than those without these conditions, according to a commentary by two neurologists. Medical providers should be trained to understand how heat waves can affect these people, the viewpoint advised. It was co-written by Indu…

Adaptive deep brain stimulation (aDBS) resulted in long-lasting relief from bradykinesia and walking difficulties in a 61-year-old Parkinson’s disease patient, whose quality of life also improved, researchers wrote in a case report about the man. Unlike conventional DBS (cDBS), where electric brain stimulation is constant or adjusted manually…

In people with Parkinson’s disease, shrinkage in tremor-related brain areas is associated with the progression of motor symptoms, according to a study. In the brain’s gray matter, which contains cell bodies of neurons, this shrinkage, or atrophy, of tremor-related regions and the whole brain over two years was associated…

Having foot pain, particularly of mild intensity or occasional pain, is associated with a higher risk of falls among people with Parkinson’s disease, a study in Spain shows. The study assessed the factors that could contribute to a higher risk of falls with Parkinson’s and found that people with…

A consortium dubbed Center Without Walls is planning to begin human testing of specific positron emission tomography (PET) radiotracers, which its scientists identified, to detect toxic proteins like alpha-synuclein, helping diagnose and monitor Parkinson’s and similar diseases. Funded by a five-year, $30 million grant from the National Institutes of…

A flexible dose of experimental oral treatment tavapadon significantly lessened motor symptoms in adults with early-stage Parkinson’s disease, according to top-line results from a completed Phase 3 clinical trial. Developer Abbvie expects to present full results of the study, TEMPO-2 (NCT04223193), at a future medical meeting and…

P2B001, Pharma Two B’s investigational combination therapy of pramipexole and rasagiline, safely and effectively lessens symptoms in people with early-stage Parkinson’s disease, according to pooled data from Phase 2b and Phase 3 clinical trials. The combo treatment was also found to be as effective as titrated extended-release pramipexole…

Axons, nerve cell projections that carry electrical signals from one cell to another, may look more like pearls on a string than the cylindrical tubes they are commonly believed to resemble, according to a study, which demonstrated that interfering with the formation of pearl-like structures impaired the transmission of electric…