Andrea Lobo,  —

IntelGenx has won approval from the Swedish Medical Products Agency (MPA) to conduct a Phase 2 trial on Montelukast Versafilm, its proprietary oral thin film formulation, in people with Parkinson’s disease. The Phase 2 MONTPARK multicenter study will investigate the effectiveness of oral high-dose Montelukast on the progression…

Cerevance has dosed the first participant in a Phase 2 clinical trial evaluating the safety and efficacy of its investigational oral therapy CVN424 for Parkinson’s disease. The ASCEND trial (NCT06006247) will explore the safety and efficacy of CVN424 as a single therapy in people with early-stage…

A pilot trial into whether deep brain stimulation based on noninvasive neuromodulation of a lower leg nerve can safely and effectively ease symptoms of Parkinson’s disease and essential tremor is fully enrolled, Stimvia, its developer, announced. The 24 patients in the study (NCT06036368) will use the company’s…

UB-312, an experimental vaccine being developed for Parkinson’s disease by Vaxxinity, induced the production of antibodies targeting alpha-synuclein and slowed protein clumping in patients’ cerebrospinal fluid (CSF), the fluid that surrounds the brain and the spinal cord. The vaccine is designed to stimulate a patient’s immune system…

Biopas Laboratories has asked the regulatory agencies of six countries in Latin America to approve Inbrija for Parkinson’s disease off periods, according to Acorda Therapeutics, the therapy’s developer and Biopas’ partner. Inbrija is a self-administered, inhaled levodopa therapy developed to reduce periods when motor symptoms are…

Chick-fil-A Dawg Bowl 2023, hosted by former Bulldogs football coach Mark Richt, has raised more than $758,000 to support research on Parkinson’s disease at the University of Georgia (UGA). Launched by a $500,000 donation from the Richt Family Foundation, all the proceeds will go to UGA’s Isakson…

A first healthy volunteer has been dosed in a Phase 1 clinical trial assessing the safety and tolerability of HL192, an investigational therapy for Parkinson’s disease. The treatment, given orally, is designed to activate Nurr1, a key protein that regulates the development and maintenance of dopaminergic neurons. These nerve…

The American Parkinson’s Disease Association (APDA) received three MM+M awards, including the titanium Best in Show, for its ParkinSex guide to help people with Parkinson’s disease and their partners retain sexual intimacy. Now in its 20th year, the MM+M Awards recognize creativity and effectiveness in…

A five-year project funded by a $5 million National Institutes of Health (NIH) research grant will study how the brain regulates movements, by allowing people with Parkinson’s disease to play video games during brain surgeries. The goal, according to researchers, is to obtain information that can be applied to…

Stem Pharm and Verge Genomics are teaming up to develop a 3D brain model of Parkinson’s disease that uses advanced computational tools to validate new therapeutic candidates. The collaboration will leverage Stem Pharm’s human-derived “mini-brains” that model inflammation of the brain — neuroimmune organoids — and Verge’s…