P2B001 may be ‘valuable’ first-line treatment for early Parkinson’s

P2B001, Pharma Two B’s investigational combination therapy of pramipexole and rasagiline, safely and effectively lessens symptoms in people with early-stage Parkinson’s disease, according to pooled data from Phase 2b and Phase 3 clinical trials. The combo treatment was also found to be as effective as titrated extended-release pramipexole…

P2B001 effective in key patient subgroups: Phase 3 trial data

P2B001, an investigational combination therapy (pramipexole/rasagiline) from Pharma Two B, controlled Parkinson’s disease symptoms better than either of its individual components regardless of patients’ age or disease severity, according to subgroup analyses from a Phase 3 trial. As with previous analyses involving all participants, P2B001 was as effective…

New Phase 3 Trial Data Back P2B001 as Therapy for Early Parkinson’s

New trial data suggest that the combination therapy P2B001 for early Parkinson’s disease may offer effective symptom control with significantly fewer side effects — notably, less daytime sleepiness — than available treatments. The therapy, being developed by the Israeli-based Pharma Two B, could potentially be a first-line,…