Mutation Affecting Myelin Protein May Raise Parkinson’s Risk

A specific genetic variant, or mutation, that is associated with an increased risk of developing amyotrophic lateral sclerosis (ALS) may also raise a person’s risk of Parkinson’s disease, a study reported. Shared features of both these neurodegenerative disorders include causative processes and “genetic backgrounds,” the researchers noted, suggesting that a mutation affecting…

Insights into Rare Disease May Lead to Novel Therapeutic Targets for Parkinson’s

The rare lysosomal storage disorder Krabbe’s disease is caused by an enzyme deficiency and has been found to have surprising similarities with neurodegenerative disorders, including Parkinson’s disease. Establishing this connection can be a valuable tool for developing novel therapeutic targets and new biomarkers for identifying patients at risk for developing Parkinson’s.