Scientists Shed Light on Workings of Mutant Alpha-synuclein Protein
A mutant form of the alpha-synuclein protein — associated with early onset, severe familial Parkinson’s disease — recruits its normal version to propagate the toxic clumps that lead to neurodegeneration, a study in mice has found. The data, specific for the E46K mutant version of alpha-synuclein, suggest that…