Apomorphine infusion, delivered by a portable device, helps to treat Parkinson’s disease and allows reduced use of other medications that may cause symptom fluctuations and treatment side effects. But in the long run, few patients are able to stay on the treatment for more than a few years, an Australian study shows. The study,…
An optimal Parkinson’s disease treatment would need to target both accelerator and brake functions in the brain to be effective without producing side effects like the jerky movements associated with L-dopa treatment. Using an advanced method to manipulate the activity in the two brain pathways that act as the accelerator…
A completely new preclinical technique developed by researchers at Lund University in Sweden involves analysis of tissue from patients to show exactly what happens in Parkinson’s disease (PD) patients who have nerve function restored as a result of nerve cell transplants. The scientists have also identified the reason why…
Recently, a group of researchers from the Columbia University Medical Center (CUMC), in New York, have identified the physiological reason why dyskinesias, the involuntary motor movements experienced by patients with Parkinson’s disease (PD) who are treated with levodopa, occurs. The study, entitled, “Loss of Striatonigral GABAergic Presynaptic Inhibition…
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