Inflammatory Markers, Sleep Disorder Linked In Parkinson’s

Blood levels of c-reactive protein (CRP) and the lymphocyte-to-monocyte ratio (LMR), two indicators of systemic inflammation, were associated with the presence of rapid eye movement (REM) sleep behavior disorder (RBD) in people with Parkinson’s disease, a study found. Patients with RBD also had worse cognition than those who did…

Anti-inflammatory Therapies May Alter Disease Course in Patients With Early-onset Parkinson’s, Study Suggests

People with early-onset Parkinson’s disease caused by mutations in the PRKN or PINK1 genes have high levels of the pro-inflammatory immune signaling protein interleukin-6 and mitochondrial DNA in the blood, which may…