Early Parkinson’s sleep disorders tied to NfL biomarker in study

The presence of sleep disorders in the earliest stages of Parkinson’s disease correlated with blood levels of neurofilament light chain (NfL), a biomarker of neurodegeneration, in a study. “This finding underscores the potential of sleep disorders as a robust clinical indicator of neuronal degeneration, closely linked with PD [Parkinson’s…

Blood Biomarker NfL May Predict Cognitive Decline

Levels of neurofilament light chain (NfL) protein in the bloodstream of people with Parkinson’s disease can independently predict cognitive decline, a recent study suggests. Although p-tau181 concentration, a biomarker in Alzheimer’s disease, which is the most common cause of dementia, was higher in Parkinson’s patients, links to cognitive performance…