Disease-modifying Parkinson’s therapy found safe in volunteers

Disease-modifying Parkinson’s therapy found safe in volunteers

ENERGI-F705PD, a potential disease-modifying therapy for Parkinson’s disease, was found to be safe and well tolerated in a Phase 1 clinical trial involving healthy volunteers, according to developer Energenesis Biomedical. Unlike currently available treatments, ENERGI-F705PD aims to address the causes of Parkinson’s and not just its symptoms.

MJFF funds promising therapy tackling Parkinson’s progression

Lysoway Therapeutics has received a $2.93-million grant from The Michael J. Fox Foundation for Parkinson’s Research (MJFF). The funding will advance a potential new therapy that targets the TRPML1 protein, a promising approach designed to modify the disease’s progression rather than just treating symptoms. “This funding underscores growing…

Personalized algorithms help improve walking in Parkinson’s

Using mathematical models, researchers at the University of California, San Francisco (UCSF) successfully predicted how to adjust deep brain stimulation (DBS) settings to improve gait for people with Parkinson’s disease, according to a study. With these techniques, researchers could improve DBS and other neuromodulatory therapies that influence nerve…

Cycling, deep stimulation may rewire brain with Parkinson’s

When combined with deep brain stimulation (DBS), a dynamic, cycling-based exercise program for people with Parkinson’s disease produces changes in brain activity indicative of potential neural rewiring, according to a study. The research was conducted at University Hospitals in Cleveland and the Veterans Affairs Northeast Ohio Healthcare System,…