Pesticide exposure linked to brain gene changes in Parkinson’s

For my husband, exercise is key to managing Parkinson’s disease

Living with an incurable neurodegenerative disease can be discouraging and frustrating. While I am thankful for medications and surgeries that provide some symptom relief and control, they have limitations. And sometimes, the side effects of the therapies are worse than the disease itself. That’s why it’s encouraging to hear that…

$5 million Fox Foundation grant targets GBA1 Parkinson’s research

The Michael J. Fox Foundation for Parkinson’s Research (MJFF) has awarded a $5 million grant to Congruence Therapeutics to advance the development of small molecules for Parkinson’s disease associated with mutations in the GBA1 gene. The research grant will support the optimization and clinical development of therapeutic candidates…

AI speech analysis detects subtle signs of Parkinson’s

Scientists at the University of Rochester have developed an artificial intelligence (AI)-powered screening tool that analyzes a person’s speech patterns to detect subtle signs of Parkinson’s disease. The algorithm could eventually be used to analyze speech patterns at home on mobile phones or household devices, helping to reach people…

Stem cell therapy eases Parkinson’s motor symptoms in trial

S.Biomedics said its stem cell-based therapy A9-DPC was found safe and effective in improving motor function over a one-year follow-up in people with Parkinson’s disease. The results apply to all 12 adults diagnosed with Parkinson’s for at least five years, who were treated with a single brain transplant…

Canada considers approval of Parkinson’s therapy Crexont

Health Canada will review Knight Therapeutics’ application seeking approval of Crexont, an extended-release formulation of levodopa and carbidopa aimed at providing steady symptom control in Parkinson’s disease, the company said. The Parkinson’s therapy is designed to maintain consistent levels of levodopa and carbidopa in the body, prolonging…