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Researchers have discovered the molecular mechanisms behind calorie restriction’s neuroprotective effect in Parkinson’s disease, and propose a new therapeutic approach that uses existing drugs to reproduce the effects demonstrated in an animal model of the disease. The study by Monash University Biomedicine Discovery Institute scientists, “Ghrelin-AMPK Signaling Mediates the Neuroprotective…

In an editorial published in the Journal of Alzheimer’s Disease, scientists and clinicians working in Alzheimer’s disease (AD) voiced concern over largely ignored research indicating that certain microbes — namely, the herpes simplex virus type 1 (HSV1), Chlamydia pneumoniae, and several types of spirochaete — might be involved in Alzheimer’s pathogenesis. The…

International Stem Cell Corporation is now enrolling patients in a Phase 1 clinical trial of its lead product candidate, ISC-hpNSC — human parthenogenetic stem cell-derived neural stem cells — for patients with moderate to severe Parkinson’s disease. Parthenogenesis uses unfertilized eggs to create pluripotent human stem cells and hopes to significantly advance the field of…