Researchers in Japan are preparing for a first human trial of induced pluripotent stem cells (iPSCs) in patients with Parkinson’s disease, after obtaining promising data from a study in monkeys. The study, which appeared in the journal Nature, demonstrated that transplanting human iPSCs into the brains of the primate…
News
The U.S. Food and Drug Administration (FDA) has given a green light to Titan Pharmaceuticals to begin a first-in-human clinical trial testing an implant that provides continuous release of ropinirole to treat Parkinson’s signs and symptoms. In the open-label Phase 1/2 trial (NCT03250117), which is now recruiting, roughly 20 Parkinson’s…
The U.S. Food and Drug Administration (FDA) will not process Acorda Therapeutics‘ marketing application for Inbrija (CVT-301), intended for the treatment of off-periods in Parkinson’s disease, until certain questions are answered. The FDA’s refusal to accept Acorda’s new drug application (NDA) for Inbrija wasn’t based on safety or efficacy concerns,…
Synthetic 3D protein structures that better mimic those in nature, but are simpler, could help scientists investigate several disorders, including Parkinson’s disease, a study indicates. The research, “Supramolecular Multiblock Copolymers Featuring Complex Secondary Structures,” appeared in the Journal of the American Chemical Society. Dr. Marcus…
Singapore Researchers, Neurosurgeons to Jointly Develop New Ways to Diagnose and Treat Parkinson’s
Singapore’s National Neuroscience Institute (NNI) and Nanyang Technological University (NTU Singapore) are teaming up to develop new technologies to better diagnose and treat patients with Parkinson’s disease, brain injuries and other neurological conditions. The collaboration aims to develop an artificial intelligence system capable of using computed tomography (CT) scans to accurately…
Gocovri Approved by FDA as 1st Treatment for Levodopa-induced Dyskinesia in Parkinson’s Patients
The first treatment for levodopa-induced dyskinesia — the involuntary and jerky movements that afflict most Parkinson’s disease patients on this common therapy — was approved Thursday, Aug. 24, by the U.S. Food and Drug Administration. The therapy, Gocovri (amantadine) by Adamas Pharmaceuticals, is an long-acting and extended-release capsule, indicated for those…
In-home senior care provider Senior Helpers has purchased Elmhurst, Illinois-based Handle with Care, a company founded by Julie Kastholm and Debbie Russell that has been providing dignified, trusted home care since 2009 to seniors in the greater Chicago area. Handle with Care’s caregivers assist their clients with everyday activities…
Internet Visits with Parkinson’s Specialist Can Be as Effective as In-person Visits, Trial Finds
Virtual house calls with a neurologist can be as effective as in-person visits for Parkinson’s disease patients, offering convenience and comfort, a clinical trial indicates. The study, “National randomized controlled trial of virtual house calls for Parkinson disease,” was published in the journal Neurology.
The biopharmaceutical company Cavion announced the appointment of a new executive vice president of research and development and chief medical officer to lead efforts advancing therapies based on the company’s T-type calcium channel (Cav3) platform targeting neurological diseases such as Parkinson’s disease (PD). Spyridon “Spyros” Papapetropoulos, MD, PhD, has been named the…
The online Parkinson’s disease community GeneFo and Greg Macpherson, MitoQ‘s CEO, will conduct a free webinar on Aug. 24, at 1 p.m. EST, to shed light on the latest results of mitochondria-targeting therapies and what the future might bring to patients suffering from Parkinson’s and other neurodegenerative diseases. In the webinar, titled…
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